Protein Alignment CG9717 and SLC26A3

DIOPT Version :10

• Sequence 1: NP_651812.1
• Gene: CG9717 / 43636
• FlyBaseID: FBgn0039789
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: NP_000102.1
• Gene: SLC26A3 / 1811
• HGNCID: 3018
• Length: 764
• Species: Homo sapiens
• Alignment Length: 605
• Identity: 146/605 - (24%)
• Similarity: 264/605 - (43%)
• Gaps: 125/605 - (20%)

  Fly    49 LEGTQSCCSNLWSNIFRKKTLYKRFPILVWLPQYK-KDYIFGDIVAGISVALTVIPQALAYAGIA 112
            |:..:.|||  .|....|:.:...|||..|||.|: |:::..|||:|||..:..:.|.||:|.:.
Human    36 LDHLKVCCS--CSPQKAKRIVLSLFPIASWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLV 98

  Fly   113 GLDLQYGLYACFLGCFIYIFIGSSKDVPIGPTAI-SALLSFQIAGGSWQ---------------- 160
            .:...|||||.|....||:|.|:|:.:.:||..| |.::...::|...:
Human    99 DIPPVYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNS 163

  Fly   161 --------------IATLLTFLTGLIEILMGVFRLGFLIDFVSGPVGAGFTSAVSLIIFSSQMKD 211
                          .|..:|.|:|:|::..|:.|:||::.::|..:.:|||:|.::.:..||:|.
Human   164 NNSSLLDDERVRVAAAASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKF 228

  Fly   212 FLGIKTSGNT----FLQVWISIVNDIHNISWPDFILGIVCITLLLSLRALASCTLGPKE-GKTTA 271
            ...:....:|    ..:|..|:.:.|...:..|.:..:: :.|::|:         .|| .:...
Human   229 IFQLTVPSHTDPVSIFKVLYSVFSQIEKTNIADLVTALI-VLLVVSI---------VKEINQRFK 283

  Fly   272 QKLLTGIFWTIGTARNALLVCGTAGLGYWL-FVNGKENLVKTVGFVPKGLPSFQPPPFHMDAVVN 335
            .||      .:......::....||:.|.. |.|..:  |..||.:.   |.||||
Human   284 DKL------PVPIPIEFIMTVIAAGVSYGCDFKNRFK--VAVVGDMN---PGFQPP--------- 328

  Fly   336 ETTGEVLQEAQSFWDMVSTLGS--GLIVVPLIALLETMAVVQAFADGKPTDATQELIASGVCNVA 398
                 :..:.::|   .:|:|.  |:.:| ..|:..::|.|.:.....|.|..|||||.|:.|:.
Human   329 -----ITPDVETF---QNTVGDCFGIAMV-AFAVAFSVASVYSLKYDYPLDGNQELIALGLGNIV 384

  Fly   399 NSFVQGLRSNGGIARGAILNASGVRTQLSNLYTSVIVIIALLYLTPCFYYIPKAALASIIIAAVI 463
            ....:|...:..::|.|:..::|.:||::.|..::||:|.:|.:......:.|:.||::.:..:.
Human   385 CGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPLQKSVLAALALGNLK 449

  Fly   464 -FMVQYRVIKPMWHSKKTDLIPGLGAFFACLVLPLQLGILVGIGINVVFILYQAARPKLRIETLA 527
             .::|:..|..:|...|.|.:..:..|...:||.|.||:...:...::.|:::...||  ..|||
Human   450 GMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGLGLGLAASVAFQLLTIVFRTQFPK--CSTLA 512

  Fly   528 T---TTGLK-----YLMLTPD-----RC---LIFPSMEF-----------------------VRK 553
            .   |...|     |.|..|:     ||   :.|.::.|                       :||
Human   513 NIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFANIGFFRRKLIDAVGFSPLRILRKRNKALRK 577

  Fly   554 V--INKQGQKSTLPVVIDCT 571
            :  :.|||.....|....||
Human   578 IRKLQKQGLLQVTPKGFICT 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9717	NP_651812.1	SUL1	82..612	CDD:440424	134/572 (23%)
SLC26A3	NP_000102.1	Sulfate_transp	73..475	CDD:459995	103/440 (23%)
		STAS_SulP_like_sulfate_transporter	526..712	CDD:132913	15/72 (21%)
		PDZ-binding. /evidence=ECO:0000269|PubMed:22627094	761..764