DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9717 and SLC26A1

DIOPT Version :9

Sequence 1:	NP_651812.1	Gene:	CG9717 / 43636	FlyBaseID:	FBgn0039789	Length:	638	Species:	Drosophila melanogaster
Sequence 2:	NP_071325.2	Gene:	SLC26A1 / 10861	HGNCID:	10993	Length:	701	Species:	Homo sapiens

Alignment Length:	518	Identity:	131/518 - (25%)
Similarity:	238/518 - (45%)	Gaps:	98/518 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 CSNLWSNIFRKKTLYKRFPILVWLPQYK-KDYIFGDIVAGISVALTVIPQALAYAGIAGLDLQYG 119
            ||...|.:..:..:....|...||.||: ::|:.||:::|:.:.:.::|||:||:.:|||...|.
Human    37 CSCSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYS 101

  Fly   120 LYACFLGCFIYIFIGSSKDVPIGPTAISALL-------SFQIAG------------------GS- 158
            ||..|....||..:|:|:.|.:|..::..|:       ..|:||                  ||
Human   102 LYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSSTLNGSA 166

  Fly   159 -----------WQIATLLTFLTGLIEILMGVFRLGFLIDFVSGPVGAGFTSAVSLIIFSSQMKDF 212
                       .::||.||.:|||.::||||.||||:..::|.|:..||....|:.|.:||:|..
Human   167 AMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGASVTILTSQLKHL 231

  Fly   213 LGIKT-----SGNTFLQVWISIVNDIHNISWPDFILGIVCITLLLSLRALASCTLGPKEGKTTAQ 272
            ||::.     .|...| .|:|::......:..|.:...||:.:||:.:.|:.         ....
Human   232 LGVRIPRHQGPGMVVL-TWLSLLRGAGQANVCDVVTSTVCLAVLLAAKELSD---------RYRH 286

  Fly   273 KLLTGIFWTIGTARNALLVCGTAGLGYWLFVNGKENLVK-----TVGFVPKG-LPSFQPPPFHMD 331
            :|...:       ...|||...|.|     |:....|.|     ..|.:|.| :|...|.|..|.
Human   287 RLRVPL-------PTELLVIVVATL-----VSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPRLMQ 339

  Fly   332 AVVNETTGEVLQEAQSFWDMVSTLGSGLIVVPLIALLETMAVVQAFA--DGKPTDATQELIASGV 394
            .|..:.                      :.:.|:|...::::.:.||  .|....|.|||:|.|.
Human   340 RVALDA----------------------VALALVAAAFSISLAEMFARSHGYSVRANQELLAVGC 382

  Fly   395 CNVANSFVQGLRSNGGIARGAILNASGVRTQLSNLYTSVIVIIALLYLTPCFYYIPKAALASIII 459
            |||..:|:....::..:|:..:..|:|.|||||::.::.:|::.||.|.|.|:.:.::.||.:|:
Human   383 CNVLPAFLHCFATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIV 447

  Fly   460 AAVIFMVQYRV--IKPMWHSKKTDLIPGLGAFFACLVLPLQLGILVGIGINVVFILYQAARPK 520
            .::...:: :|  :..:|.....|.:...|....|:::..:.|:|.|:.::::.:..:..||:
Human   448 VSLRGALR-KVWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPR 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9717	NP_651812.1	sulP	74..607	CDD:273284	128/500 (26%)
CG9717	NP_651812.1	STAS_SulP_like_sulfate_transporter	534..612	CDD:132913
SLC26A1	NP_071325.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		sulP	55..683	CDD:273284	128/500 (26%)
		STAS_SulP_like_sulfate_transporter	528..669	CDD:132913
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.810