DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9717 and slc26a11

DIOPT Version :9

Sequence 1:	NP_651812.1	Gene:	CG9717 / 43636	FlyBaseID:	FBgn0039789	Length:	638	Species:	Drosophila melanogaster
Sequence 2:	XP_002937354.2	Gene:	slc26a11 / 100486579	XenbaseID:	XB-GENE-955145	Length:	594	Species:	Xenopus tropicalis

Alignment Length:	588	Identity:	230/588 - (39%)
Similarity:	343/588 - (58%)	Gaps:	47/588 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 CLEG---------TQSCCSNLWSNIFRKKTLYKRFPILVWLPQYKKDYIFGDIVAGISVALTVIP 103
            ||||         |.:||       |...:|.||.|.|.|||:|...::..||:|||:|.|||:|
Frog     3 CLEGESCGRRLHPTLTCC-------FSCNSLQKRLPFLQWLPRYSLQWLQLDIIAGITVGLTVVP 60

  Fly   104 QALAYAGIAGLDLQYGLYACFLGCFIYIFIGSSKDVPIGPTAISALLSFQIAGGSWQIATLLTFL 168
            ||||||.:|||.:|:|||:.|:|||||.|:|:||||.:|||||.:||.|....|...:|.||||:
Frog    61 QALAYAEVAGLPVQFGLYSSFVGCFIYCFLGTSKDVTLGPTAIMSLLVFVYTLGDLSLAILLTFI 125

  Fly   169 TGLIEILMGVFRLGFLIDFVSGPVGAGFTSAVSLIIFSSQMKDFLGIKTSGNTF-LQVWISIVND 232
            :|.|::.||:...|||:||:|.||...||||.::.|..||:|:.||::.....| |||: .....
Frog   126 SGCIQLAMGLLNFGFLLDFISYPVIKAFTSAAAITIAFSQVKNLLGLQDIPRQFILQVY-QTFRK 189

  Fly   233 IHNISWPDFILGIVCITLLLSLRALASCTLGPKEGKTTAQKLLTGIFWTIGTARNALLVCGTAGL 297
            :.:....|.||||:||.:||:|:.:...|..|.:|.:...::...|.|.:.||||||:|.|...:
Frog   190 LPSTRPGDAILGILCIAILLALKWMKDHTSRPYQGMSICHRICYLIVWIMTTARNALIVVGAGLV 254

  Fly   298 GYWLFVNGKENLVKTVGFVPKGLPSFQPPPFHMDAVVNETTGEVLQEAQSFWDMVSTLGSGLIVV 362
            .|...|.|....:.| |...||||.||.||| .:...|.|        ::|.:||..:|||::::
Frog   255 AYSFHVMGLHPFILT-GKTAKGLPQFQLPPF-SEITPNGT--------KTFSEMVQVIGSGILII 309

  Fly   363 PLIALLETMAVVQAFA--DGKPTDATQELIASGVCNVANSFVQGLRSNGGIARGAILNASGVRTQ 425
            ||:.|||::|:.:|||  :.......|||:|.|:.|:..||:......|...|.|:.:.:||.|.
Frog   310 PLMGLLESVAIARAFASQNNYRIKTNQELLAIGLTNILGSFLSSYPVTGSFGRTALNSQTGVCTP 374

  Fly   426 LSNLYTSVIVIIALLYLTPCFYYIPKAALASIIIAAVIFMVQYRVIKPMWHSKKTDLIPGLGAFF 490
            ...:.|.::|:::|.||||.||:|||||||::||.||..|...|:.|.||..|:.||||    ||
Frog   375 AGGIITGLLVLLSLGYLTPAFYFIPKAALAAVIICAVAPMFDLRICKSMWKVKRLDLIP----FF 435

  Fly   491 ACLVL---PLQLGILVGIGINVVFILYQAARPKLRIETLATTTGLKYLMLTPDRCLIFPSMEFVR 552
            ...:|   .:|.|||.|..::::|:.|..|||::::      :.:..|:|||...|.||:||:::
Frog   436 VTFLLSFWEIQYGILAGTFVSIIFLCYPIARPEIKV------SDMDGLILTPMSGLSFPAMEYLK 494

  Fly   553 KVINKQGQKSTLP--VVIDCTHIYGADFTAAKVISTMVMDFKLREQPLFFYNLQPRVAQVF--EG 613
            ..|.::....:.|  |.:|.||:...|:|....::.::.:||.:...|.|..|||.:..:|  .|
Frog   495 DKIYEKTFTVSSPQSVTLDFTHVTAIDYTVVVGLAELLSEFKAQGVCLTFSGLQPPLLHMFSSSG 559

  Fly   614 LNK 616
            |.:
Frog   560 LTE 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9717	NP_651812.1	sulP	74..607	CDD:273284	216/540 (40%)
CG9717	NP_651812.1	STAS_SulP_like_sulfate_transporter	534..612	CDD:132913	25/81 (31%)
slc26a11	XP_002937354.2	sulP	31..563	CDD:273284	219/553 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	331	1.000	Domainoid score	I1160
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	408	1.000	Inparanoid score	I1836
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289441at2759
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	1	1.000	-	-		otm47848
Panther	1	1.100	-	-	O	PTHR11814
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.160