Protein Alignment Rpt6R and PSMC6

DIOPT Version :10

• Sequence 1: NP_651811.1
• Gene: Rpt6R / 43635
• FlyBaseID: FBgn0039788
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: NP_002797.4
• Gene: PSMC6 / 5706
• HGNCID: 9553
• Length: 389
• Species: Homo sapiens
• Alignment Length: 374
• Identity: 179/374 - (47%)
• Similarity: 242/374 - (64%)
• Gaps: 7/374 - (1%)

  Fly    18 YTQKISELQFTVNERQKNLLRLQAQRNELNLKVRLLREELQLLQEQGSYIAEVVKPMDKNKVLVK 82
            |.:|:.|.:    |....|..|:.|..||..:......:|:.||..|..:.||:|.:.:.|.:||
Human    12 YRKKLLEHK----EIDGRLKELREQLKELTKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVK 72

  Fly    83 VHPEGKYVVDVDKTINIKDVTPSSRVALRNESYTLHKILPNKVDPLVSLMLVEKVPDSTYEMVGG 147
            .....:|||...:.::...:.|.:||||...:.|:.:.||.:|||||..|..|...:.:|..:||
Human    73 ATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGG 137

  Fly   148 LDKQIQEIKEVIELPVKHPELFDALGITQPKGVLLYGPPGTGKTLLARAVAHHTECTFIRVSGSE 212
            |.:||:|::||||||:.:||||..:||..|||.||||||||||||||||||...:|.|::|..|.
Human   138 LSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSS 202

  Fly   213 LVQKFIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSARLETGT-GDSEVQRTMLELLNQLDGF 276
            :|.|:|||.:|::||:|..||:|.|.||||||||:||..|...|| .|.|:|||::|||||:|||
Human   203 IVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGF 267

  Fly   277 EATKNIKVIMATNRIDVLDQALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIA 341
            :....:|:||||||.|.||.|||||||:||||....|||:|||||||||:..:.....|:...|.
Human   268 DTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIV 332

  Fly   342 EEMPGASGAEVKGVCTEAGMYALRERRVHVTQEDFEMAVSKVMMKDSEK 390
            :...|.:||:::.|||||||:|:|.....|.||||..||.||  .||:|
Human   333 KLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKV--ADSKK 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpt6R	NP_651811.1	PRK03992	21..395	CDD:179699	178/371 (48%)
PSMC6	NP_002797.4	PRK03992	5..379	CDD:179699	178/372 (48%)