Protein Alignment Rpt6R and Gk

DIOPT Version :10

• Sequence 1: NP_651811.1
• Gene: Rpt6R / 43635
• FlyBaseID: FBgn0039788
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: XP_006527892.1
• Gene: Gk / 14933
• MGIID: 106594
• Length: 587
• Species: Mus musculus
• Alignment Length: 436
• Identity: 86/436 - (19%)
• Similarity: 138/436 - (31%)
• Gaps: 161/436 - (36%)

  Fly    48 LKVRLLREELQLLQEQGSYIAEVVKPMDKNKVLVKVHPEGKYVVD----------VDKTINIKDV 102
            :|:|.|.:.::.:||          .:::|:.|..       .:|          :...::..||
Mouse   180 VKLRWLLDNVKKVQE----------AVEENRALFG-------TIDSWLIWSLTGGIHGGVHCTDV 227

  Fly   103 TPSSRVALRNESYTLH----------------KILPN-----------KVDPLVSLMLVEKVP-- 138
            |.:||..|    :.:|                :||||           |:...:....:|.||
Mouse   228 TNASRTML----FNIHSLEWDKELCEFFGIPMEILPNVRSSSEIYGLMKISHSLKAGALEGVPIS 288

  Fly   139 ----DSTYEMVGGLDKQIQEIKEV------IELPVKHPELFD----------ALGITQPKGVLLY 183
                |.:..:||.:..|..:.|..      :.....|..:|.          .||..:|....|
Mouse   289 GCLGDQSAALVGQMCFQDGQAKNTYGTGCFLLCNTGHKCVFSEHGLLTTVAYKLGRDKPVYYAL- 352

  Fly   184 GPPGTGKTLLARAVAHHTECTFIRVSGSELVQKFIGEGSRMVRELFVMARE--HAP-------SI 239
                .|...:|.||..........:..||.::|...|........||.|..  :||       .|
Mouse   353 ----EGSVAIAGAVIRWLRDNLGIIKSSEEIEKLAKEVGTSYGCYFVPAFSGLYAPYWEPSARGI 413

  Fly   240 I-----FMDEIDSIGSARLETGTGDSEVQRTMLELLN----------QLDGFEATKNIKVIMATN 289
            |     |.::. .|..|.||.....:   |.:|:.:|          |:||.         |.:|
Mouse   414 ICGLTQFTNKC-HIAFAALEAVCFQT---REILDAMNRDCGIPLSHLQVDGG---------MTSN 465

  Fly   290 RIDVLDQALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAEEMPGASGAEVKG 354
            :|.:..||                      |||.|...|.::          .|......|...|
Mouse   466 KILMQLQA----------------------DILYIPVVKPSM----------PETTALGAAMAAG 498

  Fly   355 VCTEAGMYALR-ERRVHVTQEDFEMAVSKVMMKDSEKNMSIRKFWK 399
            .....|:::|. |....||.|.||   .::..::||...|.   ||
Mouse   499 AAEGVGVWSLEPEDLSAVTMERFE---PQINAEESEIRYST---WK 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpt6R	NP_651811.1	PRK03992	21..395	CDD:179699	84/430 (20%)
Gk	XP_006527892.1	ASKHA_NBD_FGGY_GK1-3-like	11..544	CDD:466802	86/436 (20%)