DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9702 and YGR125W

DIOPT Version :9

Sequence 1:	NP_001263113.1	Gene:	CG9702 / 43634	FlyBaseID:	FBgn0039787	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	NP_011641.1	Gene:	YGR125W / 853026	SGDID:	S000003357	Length:	1036	Species:	Saccharomyces cerevisiae

Alignment Length:	773	Identity:	141/773 - (18%)
Similarity:	278/773 - (35%)	Gaps:	211/773 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 VNQNLEAQFDSSSTDFIL------ITDHRTS--KSKSLEQLE----ASKESKNPESCCSRYARNI 68
            :.:|::.::....:..:|      :.|.|..  ::.||.:||    ...:|..|........||:
Yeast   131 IEENIDEEYSDEYSRLLLSPASSNVDDDRNRGLQNSSLPELEDGYAGGYQSLRPSHNLRFRPRNL 195

  Fly    69 FRKKTLLKRLPFLTWLPHYNRQDCIG---DLIAGFTVGLTVIP---QGLAYSGVVGLPPEY---- 123
            :...|     .|.:...||.....:|   :::...:.|:.:.|   ...::.|..|:...|
Yeast   196 WHMCT-----SFPSKFAHYLPAAVLGLLLNILDALSYGMIIFPITEPVFSHLGPTGISMFYISTI 255

  Fly   124 -------GLYGSF---MGC-------FVYVLLGTCKDSTIGS-TAVASLMTFQFAQGSWQRSVLL 170
                   |.:.||   :|.       |.:.:....|::..|: ..:.:...|.:        |:.
Yeast   256 ISQAVYSGGWSSFPSGIGSEMIEITPFYHTMALAIKEALAGNDDEIITTTIFCY--------VIS 312

  Fly   171 TFLTGIIEILMAIFKLGCLVEFVSGPVSAGFTSAVA--LIVSTSQMRSMLGVKSDGGSFLATW-- 231
            :.|||::...:...:||.:|.|....:..|....|.  ||::..::.:.:      ..|..:|
Yeast   313 SMLTGVVFYALGKLRLGKIVGFFPRHILIGCIGGVGYFLIITGIEVTTRV------AKFEYSWPF 371

  Fly   232 -ISMFRDIENVRVADTCLGFGCVILLLAMRSLGKFTIGPKDESRRNGFQRVVNTVIKFLSTSR-- 293
             ..:|.|.:                     :|.|:.:            .|:.||: .:.|.|
Yeast   372 FSGLFTDYD---------------------TLAKWLL------------PVLLTVV-LIGTQRYF 402

  Fly   294 -NASVVILFTAVTMYLDANGTNPFRLTGNIPKGMPTPSLPPFS----IEPQPGNETA-------- 345
             |:.|:..|..:|:.|       |.....|   :||.||....    |.|...:::.
Yeast   403 KNSLVLPSFYILTLVL-------FHFIVAI---IPTLSLDALRQAGWIFPIANSDSKWYDHYRLF 457

  Fly   346 GIPAVEG----QTFPEMVQSLGYGLVIVPLMALLETMSVCKAFAKGKQIDITQEMIACGVGNIAT 406
            .:..|..    |..|.|:....:|::.||:......||:     :..:.|:.:|:||.|..|
Yeast   458 NVHKVHWSLVLQQIPTMMALTFFGILHVPINVPALAMSL-----QMDKYDVDRELIAHGYSN--- 514

  Fly   407 SLFSGYRCNGGLARSAV--NNASGCRTNMSNLYIGVIVVLALNFLTEYIAFIPKAVLAAI---II 466
             .|||..  |.:....|  |:....|....:.:.|.:::.    ||..|..|...:::.|   |:
Yeast   515 -FFSGLL--GSVQNYLVYTNSVLFIRAGADSPFAGFLLIA----LTICIMIIGPVIISFIPICIV 572

  Fly   467 SAVIFQVQYQV----VTPMW-RSKRSDLVPGILAFVTCLVLPLEIGIMVAIGVNLLFILY----- 521
            .::||.:.|::    :...| :..|.:.:..::...|..:....:||:|.|.:.....|.
Yeast   573 GSLIFLLGYELLVEALVDTWNKLNRFEYLTVVIIVFTMGIFDFVLGIIVGILIACFSFLVDSTKL 637

  Fly   522 ---------YAARPKVTLEQLETQ------QGIRFVKITPDRCLIFP---SVEFVRNMVLKLGSK 568
                     ..||..|..:.::|:      :.|..:|:  ...|.|.   |:|.....:|::.:|
Yeast   638 QTINGEYNGNVARSTVYRDYVQTKFLDGIGEQIYVLKL--QNLLFFGTIISIEEKIERLLQISNK 700

  Fly   569 STLP-----VVIDCTYIYAAD--------------FTAAKVISSIVDDFRRRQQKIIFFNLKPSV 614
            ....     :::|...|.|.:              ||..|.|..|:...:.|.:   .:|...:|
Yeast   701 DATKRRIKYLILDFKNINADNIDYSAAEGFNRIKRFTETKRIKLIISSIKERDR---IYNAFNNV 762

  Fly   615 -----VSVFEGLNTRLVLCYNTHALN-QELRPDEPDLSRSVDSLDHAESGNGTSECVS 666
                 |.:|..||:.|..|.|..... ::||      .::.:.|:..:..|..|..::
Yeast   763 GLLNDVELFADLNSALEWCENEFLFQYKQLR------KKAKERLEEGKQNNVVSAVIA 814

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9702	NP_001263113.1	SUL1	72..614	CDD:223732	116/645 (18%)
CG9702	NP_001263113.1	STAS_SulP_like_sulfate_transporter	531..619	CDD:132913	21/120 (18%)
YGR125W	NP_011641.1	SUL1	128..785	CDD:223732	136/736 (18%)
YGR125W	NP_011641.1	CAP_ED	910..1014	CDD:237999
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810