DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9702 and Slc26a5

DIOPT Version :9

Sequence 1:	NP_001263113.1	Gene:	CG9702 / 43634	FlyBaseID:	FBgn0039787	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	NP_110467.1	Gene:	Slc26a5 / 83819	RGDID:	69334	Length:	744	Species:	Rattus norvegicus

Alignment Length:	548	Identity:	142/548 - (25%)
Similarity:	255/548 - (46%)	Gaps:	112/548 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 KNPESCCSRYARNIFRKKTLLKRLPFLTWLPHYN-RQDCIGDLIAGFTVGLTVIPQGLAYSGVVG 118
            |...:|..:..|||     :...||...|||.|. ::..:|||::|.:.|:..:|||||::.:..
  Rat    47 KQAFTCTPKKVRNI-----IYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAA 106

  Fly   119 LPPEYGLYGSFMGCFVYVLLGTCKDSTIGSTAVASLMTFQFA-----------------QGSWQR 166
            :||.:|||.||....:|...||.:..:||..||.|||....|                 .|:..|
  Rat   107 VPPVFGLYSSFYPVIMYCFFGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEAR 171

  Fly   167 SVL-------LTFLTGIIEILMAIFKLGCLVEFVSGPVSAGFTSAVALIVSTSQMRSMLGVKSD- 223
            ..|       :|.|:|||:..:.:.:.|.:..:::.|:..|||:|.|:.|.||.::.:.|||:.
  Rat   172 DALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKR 236

  Fly   224 -GGSFLATW--ISMFRDIENVRVADTCLGFGCVILLLAMRSLGKFTIGPKDESRRNGFQRVVNTV 285
             .|.|...:  :::.::::|:.|..  ||.|.::..|        .:|.|:.:.|...:......
  Rat   237 YSGIFSVVYSTVAVLQNVKNLNVCS--LGVGLMVFGL--------LLGGKEFNERFKEKLPAPIP 291

  Fly   286 IKFLSTSRNASVVILFTAVTMYLDANGTNPFRLTGNIPKGMPTPSLPPFSIEPQPGNETAGIPAV 350
            ::|.:       |::.|.::...:.:.:....:.|.:|.|:..|:.|..|:
  Rat   292 LEFFA-------VVMGTGISAGFNLHESYSVDVVGTLPLGLLPPANPDTSL-------------- 335

  Fly   351 EGQTFPEMVQSLGYGLVIVPLMALL-----ETMSVCKAFAK--GKQIDITQEMIACGVGNIATSL 408
                         :.||.|..:|:.     .|:|:.|..|.  |.|:|..||:||.|:.|...||
  Rat   336 -------------FHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGICNSIGSL 387

  Fly   409 FSGYRCNGGLARSAVNNASGCRTN----MSNLYIGVIVVLALNFLTEYIAFIPKAVLAAIIISAV 469
            |..:..:..|:||.|...:|.:|.    :::|.| ::|:||..||.|   .:|:|||:||:|..:
  Rat   388 FQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMI-LLVILATGFLFE---SLPQAVLSAIVIVNL 448

  Fly   470 --IFQVQYQVVTPMWRSKRSDLVPGILAFVTCLVLPLEIGIMVAIGVNLLFILYYAARPKVTL-- 530
              :| :|:..:...||:.:.:|...:..||:.|.|.|:.|::.|:.:.||.::|....|..|:
  Rat   449 KGMF-MQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYTVLG 512

  Fly   531 --------------EQLETQQGIRFVKI 544
                          |:::...||:..:|
  Rat   513 QLPDTDVYIDIDAYEEVKEIPGIKIFQI 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9702	NP_001263113.1	SUL1	72..614	CDD:223732	137/531 (26%)
CG9702	NP_001263113.1	STAS_SulP_like_sulfate_transporter	531..619	CDD:132913	4/14 (29%)
Slc26a5	NP_110467.1	sulP	66..709	CDD:273284	136/524 (26%)
		STAS_SulP_like_sulfate_transporter	526..694	CDD:132913	4/15 (27%)
		STAS	589..>683	CDD:279997
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	720..744
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.710