Protein Alignment CG9702 and Slc26a5

DIOPT Version :10

• Sequence 1: NP_651810.1
• Gene: CG9702 / 43634
• FlyBaseID: FBgn0039787
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_109652.3
• Gene: Slc26a5 / 80979
• MGIID: 1933154
• Length: 744
• Species: Mus musculus
• Alignment Length: 738
• Identity: 166/738 - (22%)
• Similarity: 306/738 - (41%)
• Gaps: 195/738 - (26%)

  Fly    41 KSKSLEQLEASKESKNPESCCSRYARNIFRKKTLLKRLPFLTWLPHYN-RQDCIGDLIAGFTVGL 104
            |.|..|.:  ..:.|...:|..:..|||     :...||...|||.|. ::..:|||::|.:.|:
Mouse    35 KDKVTESI--GDKLKQAFTCTPKKIRNI-----IYMFLPITKWLPAYKFKEYVLGDLVSGISTGV 92

  Fly   105 TVIPQGLAYSGVVGLPPEYGLYGSFMGCFVYVLLGTCKDSTIGSTAVASLMTFQFA--------- 160
            ..:|||||::.:..:||.:|||.||....:|...||.:..:||..||.|||....|
Mouse    93 LQLPQGLAFAMLAAVPPVFGLYSSFYPVIMYCFFGTSRHISIGPFAVISLMIGGVAVRLVPDDIV 157

  Fly   161 --------QGSWQRSVL-------LTFLTGIIEILMAIFKLGCLVEFVSGPVSAGFTSAVALIVS 210
                    .|:..|..|       :|.|:|||:..:.:.:.|.:..:::.|:..|||:|.|:.|.
Mouse   158 IPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVF 222

  Fly   211 TSQMRSMLGVKSD--GGSFLATW--ISMFRDIENVRVADTCLGFGCVILLLAMRSLGKFTIGPKD 271
            ||.::.:.|||:.  .|.|...:  :::.::::|:.|..  ||.|.::..|        .:|.|:
Mouse   223 TSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCS--LGVGLMVFGL--------LLGGKE 277

  Fly   272 ESRRNGFQRVVNTVIKFLSTSRNASVVILFTAVTMYLDANGTNPFRLTGNIPKGMPTPSLPPFSI 336
            .:.|...:......::|.:       |::.|.::...:.:.:....:.|.:|.|:..|:.|..|:
Mouse   278 FNERFKEKLPAPIPLEFFA-------VVMGTGISAGFNLHESYSVDVVGTLPLGLLPPANPDTSL 335

  Fly   337 EPQPGNETAGIPAVEGQTFPEMVQSLGYGLVIVPLMALL-----ETMSVCKAFAK--GKQIDITQ 394
                                       :.||.|..:|:.     .|:|:.|..|.  |.|:|..|
Mouse   336 ---------------------------FHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQ 373

  Fly   395 EMIACGVGNIATSLFSGYRCNGGLARSAVNNASGCRTN----MSNLYIGVIVVLALNFLTEYIAF 455
            |:||.|:.|...|||..:..:..|:||.|...:|.:|.    :::|.| ::|:||..||.|   .
Mouse   374 ELIALGICNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMI-LLVILATGFLFE---S 434

  Fly   456 IPKAVLAAIIISAV--IFQVQYQVVTPMWRSKRSDLVPGILAFVTCLVLPLEIGIMVAIGVNLLF 518
            :|:|||:||:|..:  :| :|:..:...||:.:.:|...:..||:.|.|.|:.|::.|:.:.||.
Mouse   435 LPQAVLSAIVIVNLKGMF-MQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLT 498

  Fly   519 ILYYAARPKVTL----------------EQLETQQGIRFVKITPD---------------RCLIF 552
            ::|....|...:                |:::...||:..:|...               :..:.
Mouse   499 VIYRTQSPSYKVLGQLPDTDVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSSALKRKTGVN 563

  Fly   553 PSV------EFVRNMVLKLGS-------------------------------------KSTLP-- 572
            |::      :.:|....::|:                                     |:|.|
Mouse   564 PALIMGARRKAMRKYAKEVGNANVANATVVKVDAEVDGENATKPEEEDDEVKFPPIVIKTTFPEE 628

  Fly   573 -------------VVIDCTYIYAADFTAAKVISSIVDDFRRRQQKIIFFNLKPSVV------SVF 618
                         |::|.|.:...|....|.::.||.::......:......|.||      :.|
Mouse   629 LQRFLPQGENVHTVILDFTQVNFVDSVGVKTLAGIVKEYGDVGIYVYLAGCSPQVVNDLTRNNFF 693

  Fly   619 EGLNTRLVLCYNTH--ALNQELR 639
            |....:.:|.::.|  .|..::|
Mouse   694 ENPALKELLFHSIHDAVLGSQVR 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9702	NP_651810.1	SUL1	86..619	CDD:440424	147/669 (22%)
Slc26a5	NP_109652.3	PRK11660	66..709	CDD:481320	155/691 (22%)
		Involved in motor function. /evidence=ECO:0000250|UniProtKB:Q9JKQ2	158..168		0/9 (0%)
		Extended region for STAS domain. /evidence=ECO:0000250|UniProtKB:Q9EPH0	505..718		27/212 (13%)
		STAS_anti-anti-sigma_factors	589..683	CDD:132914	11/93 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	720..744