DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9702 and slc26a6

DIOPT Version :9

Sequence 1:	NP_001263113.1	Gene:	CG9702 / 43634	FlyBaseID:	FBgn0039787	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	NP_001072916.2	Gene:	slc26a6 / 780378	XenbaseID:	XB-GENE-919879	Length:	735	Species:	Xenopus tropicalis

Alignment Length:	600	Identity:	150/600 - (25%)
Similarity:	271/600 - (45%)	Gaps:	135/600 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 AQFDSSSTDFILITDHRTSKSKSLEQLEASKESKNPESCCSRYARNI-----FRKKTLLKRLPFL 81
            |..|.::...:|       ....||::....:...| |..:|..:.|     ..|..|||.:|.|
Frog    14 AVMDPAARQLVL-------SEAELEEIAPRSQRVGP-STLARMKKRIRCSGSIAKSLLLKFIPIL 70

  Fly    82 TWLPHYN-RQDCIGDLIAGFTVGLTVIPQGLAYSGVVGLPPEYGLYGSFMGCFVYVLLGTCKDST 145
            .|:|.|. |:..:||::||.:||:..:||||||:.:.|:||.||||.||....:|.:.||.:..:
Frog    71 GWIPRYPVREWLLGDIVAGLSVGIIQLPQGLAYALLAGVPPVYGLYSSFFPVLLYAIFGTSRHIS 135

  Fly   146 IGSTAVASLMTFQFAQGSWQRSVL-----------------------------LTFLTGIIEILM 181
            .|:.||.|:|.     ||...|::                             ||||.|:.:|::
Frog   136 PGTFAVISVMV-----GSVTESLVPSELYTLPGNETLINITARDNDRVAVASALTFLVGLFQIML 195

  Fly   182 AIFKLGCLVEFVSGPVSAGFTSAVALIVSTSQMRSMLGV----KSDGGSFLATWISMFRDIENVR 242
            .:.::|.:|.::|.|:..|:|||.|:.|:.|||:|:|||    :|...|.:...:::...:....
Frog   196 GLVQVGFVVTYLSEPLIRGYTSAAAIHVTVSQMKSVLGVQISQRSHPLSLIYAIVNLCAKLPETN 260

  Fly   243 VADTCLGFGCVILLLAMRSLGKFTIGPKDESRRNGFQRVVNTVIKFLSTSRNASV---------- 297
            :|...:| |..|.:|                          .|:|||:...::.:
Frog   261 IASLLIG-GIAITVL--------------------------FVVKFLNDKYSSKIRMPIPIELIT 298

  Fly   298 VILFTAVTMYLDANGTNPFRLTGNIPKGMPTPSLPPFSIEPQPGNETAGIPAVEGQTFPEMVQSL 362
            :|:.|.::...:.|......:.|.||.||..|.:|..||          ..:|.|..|
Frog   299 LIVATGISYGANLNQVYGVDIVGEIPTGMKAPMVPNASI----------FASVVGNAF------- 346

  Fly   363 GYGLVIVPLMALLETMSVCKAFA--KGKQIDITQEMIACGVGNIATSLFSGYRCNGGLARSAVNN 425
                 .:.::....|:|:.|.||  .|..:|..||:||.|:.|...|.|..:.....::||.|..
Frog   347 -----AIAVVVYAFTISLAKMFAVKHGYNVDSNQELIALGLSNSIGSFFQCFTIGTAMSRSLVQE 406

  Fly   426 ASGCRTNMSNLYIGVIVVLALNFLTEYIAFIPKAVLAAIIISAV--IFQVQYQVVTPMWRSKRSD 488
            ::|..:.:::....:::::.:....|....:|||:|||:::..:  |:: |:..|..:|||.:.|
Frog   407 STGGHSQVASAVSSLVILIIILRAGELFQTLPKAILAAVVVVNLKGIYK-QFTDVPMLWRSNKID 470

  Fly   489 LVPGILAFVTCLVLPLEIGIMVAIGVNLLFILYYAARPKVTL----------------EQLETQQ 537
            |:..::.|:..::|.|:||:.|::..:||.:::...:|..::                :|:...|
Frog   471 LLVWVVTFLATILLNLDIGLAVSVAFSLLTVIFRTQKPHYSILGKVDNTDIYRDVAQFDQVTEIQ 535

  Fly   538 GIRFVKITPDRCLIF 552
            ||   ||....|.::
Frog   536 GI---KIFRSSCTLY 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9702	NP_001263113.1	SUL1	72..614	CDD:223732	140/544 (26%)
CG9702	NP_001263113.1	STAS_SulP_like_sulfate_transporter	531..619	CDD:132913	7/21 (33%)
slc26a6	NP_001072916.2	sulP	68..711	CDD:273284	137/537 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910