DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9702 and slc26a2

DIOPT Version :9

Sequence 1:	NP_001263113.1	Gene:	CG9702 / 43634	FlyBaseID:	FBgn0039787	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	XP_005173217.1	Gene:	slc26a2 / 557046	ZFINID:	ZDB-GENE-030717-3	Length:	699	Species:	Danio rerio

Alignment Length:	716	Identity:	163/716 - (22%)
Similarity:	279/716 - (38%)	Gaps:	176/716 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 LEQLEASKES------KNPESCCSRYARNIFRKKTLLKRLPFLTWLPHYNRQD-CIGDLIAGFTV 102
            ||:....|.|      |..:.|....||   .|..::|..|.:.|||.|..:| .|||.::|..|
Zfish    26 LEECVKEKVSWKEALRKKVKKCSCSTAR---VKSQIMKSFPIVKWLPRYRFKDWIIGDAMSGLIV 87

  Fly   103 GLTVIPQGLAYSGVVGLPPEYGLYGSFMGCFVYVLLGTCKDSTIGSTAVASLMTFQFAQ------ 161
            |:.::||.:|||.:.|..|.||||.||....:|.||||.:..::|...|..|:..|...
Zfish    88 GILLVPQSIAYSLLAGQDPIYGLYTSFFANIIYALLGTSRHISVGMFGVLCLLVGQVVDRELTLA 152

  Fly   162 -----------GSWQRS---------------VLLTFLTGIIEILMAIFKLGCLVEFVSGPVSAG 200
                       |:...|               ..|||..||.::||.:.::|.:..|:|..:.:|
Zfish   153 GYSSDINQTTLGNVDNSTGPICDRSCYAIMVGATLTFTAGIYQVLMGLLQIGFVSVFLSDSLLSG 217

  Fly   201 FTSAVALIVSTSQMRSMLGV---KSDG-GSFLATWISMFRDIENVRVADTCLGFGCVILLLAMRS 261
            |.:..:|.:.|||::..||:   :..| ||.:.||||:|:::.:..:.|......|:::|:..:.
Zfish   218 FATGASLTILTSQIKYFLGLHLPRVQGWGSLIKTWISLFKNLGHTNLCDLITSLICLLVLVPAKE 282

  Fly   262 LGKFTIGPKDESRRNGFQRVVNTVIKFLSTSRNASVVILFTAVTMYLDANGTNPFRLTGNIPKGM 326
            |            .:.|:..:...|.|     ...|||..|..:.:.....|....:.|.||.|.
Zfish   283 L------------NDRFKAKLKAPIPF-----ELFVVIAATLASHFGHFKDTYGSDVAGTIPTGF 330

  Fly   327 PTPSLPPFSIEPQPGNETAGIPAVEGQTFPEMVQSLGYGLVIVPLMALLETMSVCKAFAK--GKQ 389
            ..|..|..|:.|....:...|..|            |:.:          |:|:.:.|||  |..
Zfish   331 MAPQSPNLSLVPNIAIDALSIAIV------------GFAI----------TVSLSEMFAKKHGYI 373

  Fly   390 IDITQEMIACGVGNIATSLFSGYRCNGGLARSAVNNASGCRTNMSNLYIGVIVVLALNFLTEYIA 454
            ::..||:.|.|..||.:|.|..:..:..|.::.|..::||.|.:|.|...::::|.:..:.....
Zfish   374 VNANQELNAIGNCNIISSYFHCFTVSAALTKTLVKESTGCHTQISGLVTALVLLLVMLVIAPAFY 438

  Fly   455 FIPKAVLAAIIISAVIFQV-QYQVVTPMWRSKRSDLVPGILAFVTCLVLPLEIGIMVAIGVNLLF 518
            .:.|.|||.||:..:...: ::..:..|||..|.|.|..:|...|..::..|:|::|.:.|:...
Zfish   439 SLQKCVLAVIIVVNLRGALRKFGDIPQMWRVNRVDTVIWLLTMATSALVNTELGLLVGVVVSAFC 503

  Fly   519 IL--------------------------------------------YYA---------------- 523
            :|                                            |||
Zfish   504 VLGRTQFAQALQLGQAGDRELFEDIASYNGLQTQPDVAVFRYEAPIYYANQSLFKKSLYRNVGLD 568

  Fly   524 -ARPKVTLEQLETQQGIRFVKITPDRCLIFPSVEFVRNM-VLKLGSKSTLPVVIDCTYIYAADFT 586
             .:.|....:||.|:..:..:....:     .::...|: :|:..|..||  ||||:.:...|..
Zfish   569 PLKEKAKQRKLEKQRKQKHSREDQKQ-----EMDASTNVNLLQHSSFHTL--VIDCSSVLFLDTA 626

  Fly   587 AAKVISSIVDDFRRRQQKIIFFNLKPSVVSVFEGLNTRLVLCYNTHALNQELRPDEPDLSRSVDS 651
            ....:..:..|::..                  |:|..|..| ||..::...|.|..|.::....
Zfish   627 GVNALKEVFKDYKEL------------------GVNVLLAQC-NTSVIDSLRRGDYYDPNKGTKD 672

  Fly   652 L 652
            :
Zfish   673 I 673

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9702	NP_001263113.1	SUL1	72..614	CDD:223732	145/643 (23%)
CG9702	NP_001263113.1	STAS_SulP_like_sulfate_transporter	531..619	CDD:132913	14/88 (16%)
slc26a2	XP_005173217.1	sulP	63..681	CDD:273284	153/676 (23%)
slc26a2	XP_005173217.1	STAS_SulP_like_sulfate_transporter	531..665	CDD:132913	26/159 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810