DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9702 and slc26a11

DIOPT Version :9

Sequence 1:	NP_001263113.1	Gene:	CG9702 / 43634	FlyBaseID:	FBgn0039787	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	NP_956061.1	Gene:	slc26a11 / 327138	ZFINID:	ZDB-GENE-030131-5349	Length:	572	Species:	Danio rerio

Alignment Length:	603	Identity:	213/603 - (35%)
Similarity:	310/603 - (51%)	Gaps:	51/603 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 PESCCSRYARNIFRKKTLLKRLPFLTWLPHYNRQDCIGDLIAGFTVGLTVIPQGLAYSGVVGLPP 121
            |..|.....|:.|         |.:||||.||......|:|||.|||||.:||.|||:.|.|||.
Zfish     3 PHICWFPALRSCF---------PIITWLPRYNLTWLKMDVIAGLTVGLTAVPQALAYAEVAGLPV 58

  Fly   122 EYGLYGSFMGCFVYVLLGTCKDSTIGSTAVASLMTFQFAQGSWQRSVLLTFLTGIIEILMAIFKL 186
            :||||.:|||.|:|.:.||.||.|:|.||:.||:...:..|....:|:||.|.|:|:..||:.:|
Zfish    59 QYGLYSAFMGGFIYCIFGTSKDITLGPTAIMSLLCSSYITGDPVFAVVLTLLCGVIQTGMALLRL 123

  Fly   187 GCLVEFVSGPVSAGFTSAVALIVSTSQMRSMLGVKSDGGSFLATWISMFRDIENVRVADTCLGFG 251
            |.|::|:|.||..|||.|.|:.:...|::::||:|.....|.......|..|...||.|..||..
Zfish   124 GFLLDFISYPVIKGFTCAAAVTIGFGQVKNILGLKEIPQQFFLQVYYTFHKIPEARVGDVILGLS 188

  Fly   252 CVILLLAMRSLGKFTIGPKDESRRNGFQRVVNTVIKFLSTSRNASVVILFTAVTMYLDANGTNPF 316
            |:..||.:..:.......:||:  :...|....::..|:|.|||.|||....|....:..|.:.|
Zfish   189 CLFFLLILTFMKNSLNSAEDEA--SFLVRSARQLLWSLATIRNALVVIAAAGVAFSAEVTGNHFF 251

  Fly   317 RLTGNIPKGMPTPSLPPFSIEPQPGNETAGIPAVEGQTFPEMVQSLGYGLVIVPLMALLETMSVC 381
            .|||...||:|....||.|       ||.....|  .||.::.:.||.||.::|||.:||::::.
Zfish   252 SLTGKTAKGLPPFRAPPLS-------ETIANGTV--ITFSDIAKDLGGGLAVIPLMGVLESIAIA 307

  Fly   382 KAFA--KGKQIDITQEMIACGVGNIATSLFSGYRCNGGLARSAVNNASGCRTNMSNLYIGVIVVL 444
            |||.  ...:||..||:.|.|:.||..|..|.|...|...|:|||:.:|..:....:...|||:|
Zfish   308 KAFGSKNNYRIDANQELFAIGLTNIMGSFVSAYPVTGSFGRTAVNSQTGVCSPAGGIITSVIVLL 372

  Fly   445 ALNFLTEYIAFIPKAVLAAIIISAVIFQVQYQVVTPMWRSKRSDLVPGILAFVTCLVLPLEIGIM 509
            :|.||.....:||||.|||:||.||...|.::|...:||.||.||:|.::.|:... ..::.||.
Zfish   373 SLAFLMPLFFYIPKASLAAVIICAVSPMVDFRVPLHIWRVKRLDLLPFLVTFLLSF-WEVQYGIA 436

  Fly   510 VAIGVNLLFILYYAARPKVTLEQLETQQGIRFVKITPDRCLIFPSVEFVRNMVLKLGSKSTLP-- 572
            ..:.|:...:||..|||||.:    :..|:..::|  |..|.|.|.|.:..:|.|....::.|
Zfish   437 GGVLVSAFMLLYIMARPKVKV----SDHGVIVLEI--DNGLNFTSTEHLSRLVYKHALHASPPRS 495

  Fly   573 VVIDCTYIYAADFTAAKVISSIVDDFRRRQQKIIFFNLKPSVVSVFEGLNTRLVLCYNTHALNQE 637
            :|:||:.|.:.|||....::.::..|:.|...:||..|||||:.|.
Zfish   496 LVLDCSQISSIDFTVIHELTDLLKQFQIRGAALIFTGLKPSVLQVL------------------- 541

  Fly   638 LRPDEPDLSRSVDSLDHA 655
            |..|.|.. |..|::|.|
Zfish   542 LLADLPAF-RHTDTVDEA 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9702	NP_001263113.1	SUL1	72..614	CDD:223732	199/545 (37%)
CG9702	NP_001263113.1	STAS_SulP_like_sulfate_transporter	531..619	CDD:132913	27/89 (30%)
slc26a11	NP_956061.1	sulP	16..541	CDD:273284	201/542 (37%)
slc26a11	NP_956061.1	STAS_SulP_like_sulfate_transporter	454..546	CDD:132913	30/116 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574467
Domainoid	1	1.000	46	1.000	Domainoid score	I12111
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289441at2759
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	1	1.100	-	-	O	PTHR11814
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.710