DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9702 and slc26a5

DIOPT Version :9

Sequence 1:	NP_001263113.1	Gene:	CG9702 / 43634	FlyBaseID:	FBgn0039787	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	NP_958881.1	Gene:	slc26a5 / 322846	ZFINID:	ZDB-GENE-030131-1566	Length:	739	Species:	Danio rerio

Alignment Length:	758	Identity:	185/758 - (24%)
Similarity:	318/758 - (41%)	Gaps:	201/758 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 EAQFDSSSTDFILITDHRTSKSKSLEQLEASKESKNPESCCSRYARNIFRKKTLLKRLPFLTWLP 85
            ||..||...       |:..|:....:|..::     ..|||  :..:  |..:...||.|||||
Zfish    25 EAYIDSELL-------HKRKKTPKPYKLRVAE-----HLCCS--SEKV--KSVVFGFLPILTWLP 73

  Fly    86 HYNRQDCI-GDLIAGFTVGLTVIPQGLAYSGVVGLPPEYGLYGSFMGCFVYVLLGTCKDSTIGST 149
            .|..::.: ||:::|.:.|:..:||||||:.:..:||.:|||.||....:|...||.|..:||:.
Zfish    74 SYPLKEYLFGDIVSGISTGVMQLPQGLAYAMLAAVPPVFGLYSSFYPVLLYTFFGTSKHISIGTF 138

  Fly   150 AVASLM----------TFQFAQGSWQRS----------------VLLTFLTGIIEILMAIFKLGC 188
            ||.|||          ...|.......|                |.||.|.|||:.::.:.:.|.
Zfish   139 AVISLMIGGVAVREAPDSMFMVNGTNSSLVVNIEARDSRRVEVVVALTTLVGIIQFVLGLLRFGF 203

  Fly   189 LVEFVSGPVSAGFTSAVALIVSTSQMRSMLGVKS---DGG-SFLATWISMFRDIENVRVADTCLG 249
            |..:::.|:..|||:|.|:.||.||::.:||||:   :|. |.:.:..::.|:|.:..:....:|
Zfish   204 LAIYLTEPLVRGFTTAAAVHVSVSQLKYLLGVKTARFNGPLSVVYSLDAVLRNIADTNIVTLIIG 268

  Fly   250 FGCVILLLAMRSLGKFTIGPKDESRRNGFQRVVNTVIKFLSTSRNASVVILFTAVT--MYLDAN- 311
            .||.:.|..::.|       .:..::.....:...:|          |||:.|.::  |.:..|
Zfish   269 LGCTVFLYIIKQL-------NERFKKKLLIPIPGEII----------VVIVSTGISYGMLMSENY 316

  Fly   312 GTNPFRLTGNIPKGMPTPSLPPFSIEPQPGNETAGIPAVEGQTFPEMVQSLGYGLVIVPLMALLE 376
            |.:   :.|.||.|:..|.:|.||:.|....:...|..|            |:.:
Zfish   317 GVD---VVGKIPTGLLPPKVPDFSVFPNLFADAVPIAVV------------GFSI---------- 356

  Fly   377 TMSVCKAFA--KGKQIDITQEMIACGVGNIATSLFSGYRCNGGLARSAVNNASGCRTNMSNL--- 436
            |:|:.|.||  .|..:|..||:||.|:.|..:|.|..:.....::||.|..::|..|.::.|
Zfish   357 TISLAKTFALKYGYSVDGNQELIALGLCNFVSSFFHTFVVTASMSRSLVQESTGGHTEIAGLLAS 421

  Fly   437 YIGVIVVLALNFLTEYIAFIPKAVLAAIIISAVI--FQVQYQVVTPMWRSKRSDLVPGILAFVTC 499
            .:.::||:|:.|:.:.   :|..||||||:..::  |: |.:.:..:||..:.:|...:::|...
Zfish   422 LLVLLVVVAIGFVFQP---LPTTVLAAIIMVNLLGMFK-QTRDIPVLWRKSKIELAIWLVSFFAS 482

  Fly   500 LVLPLEIGIMVAIGVNLLFILYYAARPK-VTL---------------EQLETQQGIR-------- 540
            ::|.|:.|:.||:...:|.::|...||| |.|               |:.|...||:
Zfish   483 VLLGLDYGLAVAMAFAILTVIYRTQRPKNVVLGQIPDTGLYFDVDEYEEAEECSGIKIFQSNSSI 547

  Fly   541 -------FVK-------ITPDRCLIFPSVEFVRNMVLKLGSKST---------------LPVVID 576
                   :||       |.|::.|      ..:.:.||...:.|               ..|::|
Zfish   548 YFANSELYVKALKAKTGIDPEKLL------DAKKLQLKYAKRDTEGTKTVNQGSLLKKNAVVLLD 606

  Fly   577 C---------------TYIYAADFTAAKVISSIVDD--FRRRQQKI--IFFNLKP---------- 612
            .               .:::.......|.|.|..:|  |.:|...|  :..:..|
Zfish   607 MELGVTHEVLNGPQKPKHVHTNGQMTEKHIESESEDEFFLQRLTPIHSVILDFTPVNFIDSVGAK 671

  Fly   613 ---SVVSVFEGLNTRLVLCYNTHALNQELR-------PDEPDL 645
               ||:..:..::.::||...:..|..|||       |..|||
Zfish   672 TIKSVIKEYATVDVKVVLAGCSRTLLSELRTLQFFSEPVTPDL 714

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9702	NP_001263113.1	SUL1	72..614	CDD:223732	162/667 (24%)
CG9702	NP_001263113.1	STAS_SulP_like_sulfate_transporter	531..619	CDD:132913	24/156 (15%)
slc26a5	NP_958881.1	sulP	67..722	CDD:273284	173/700 (25%)
		LrgB	259..>366	CDD:294396	29/148 (20%)
		STAS_SulP_like_sulfate_transporter	<643..719	CDD:132913	16/72 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.710