DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9702 and SLC26A11

DIOPT Version :9

Sequence 1:	NP_001263113.1	Gene:	CG9702 / 43634	FlyBaseID:	FBgn0039787	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	XP_016879994.1	Gene:	SLC26A11 / 284129	HGNCID:	14471	Length:	696	Species:	Homo sapiens

Alignment Length:	609	Identity:	216/609 - (35%)
Similarity:	329/609 - (54%)	Gaps:	60/609 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 SKSKSLEQLEASKESKNPESCCSRYARNIFRKKTLLKRLPFLTWLPHYNRQDCIGDLIAGFTVGL 104
            |...:|.|..:|.....|.:||...|       .|.:|||.|.|||.|:.|....|.:||.:|||
Human    69 SSVTALGQARSSGPGMAPSACCCSPA-------ALQRRLPILAWLPSYSLQWLKMDFVAGLSVGL 126

  Fly   105 TVIPQGLAYSGVVGLPPEYGLYGSFMGCFVYVLLGTCKDSTIGSTAVASLMT--FQFAQGSWQRS 167
            |.|||.|||:.|.||||:||||.:|||||||..|||.:|.|:|.||:.||:.  :.|.:.::  :
Human   127 TAIPQALAYAEVAGLPPQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFHEPAY--A 189

  Fly   168 VLLTFLTGIIEILMAIFKL------------------------GCLVEFVSGPVSAGFTSAVALI 208
            |||.||:|.|::.|.:.:|                        |.|::|:|.||..|||||.|:.
Human   190 VLLAFLSGCIQLAMGVLRLAHISPHPLGLGGAGTSSMSPLGWPGFLLDFISYPVIKGFTSAAAVT 254

  Fly   209 VSTSQMRSMLGVKSDGGSFLATWISMFRDIENVRVADTCLGFGCVILLLAMRSLGKFTIGPKDES 273
            :...|::::||:::....|.......|..|...||.|..||..|::|||.:: |.:..:.|....
Human   255 IGFGQIKNLLGLQNIPRPFFLQVYHTFLRIAETRVGDAVLGLVCMLLLLVLK-LMRDHVPPVHPE 318

  Fly   274 RRNGFQRVVNTVIKFLSTSRNASVVILFTAVTMY-LDANGTNPFRLTGNIPKGMPTPSLPPFSIE 337
            ...|. |:...::...:|:||| :|:.|.|:..| .:..|..||.|||...:|:|...:||||:.
Human   319 MPPGV-RLSRGLVWAATTARNA-LVVSFAALVAYSFEVTGYQPFILTGETAEGLPPVRIPPFSVT 381

  Fly   338 PQPGNETAGIPAVEGQTFPEMVQSLGYGLVIVPLMALLETMSVCKAFA--KGKQIDITQEMIACG 400
            ...|.          .:|.||||.:|.||.:||||.|||:::|.||||  ...:||..||::|.|
Human   382 TANGT----------ISFTEMVQDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQELLAIG 436

  Fly   401 VGNIATSLFSGYRCNGGLARSAVNNASGCRTNMSNLYIGVIVVLALNFLTEYIAFIPKAVLAAII 465
            :.|:..||.|.|...|...|:|||..||..|....|..||:|:|:|::||....:|||:.|||:|
Human   437 LTNMLGSLVSSYPVTGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYIPKSALAAVI 501

  Fly   466 ISAVIFQVQYQVVTPMWRSKRSDLVPGILAFVTCLVLPLEIGIMVAIGVNLLFILYYAARPKVTL 530
            |.||......::...:||.||.||:|..:.|:.|. ..::.||:....|:||.:|:.||||
Human   502 IMAVAPLFDTKIFRTLWRVKRLDLLPLCVTFLLCF-WEVQYGILAGALVSLLMLLHSAARP---- 561

  Fly   531 EQLETQQGIRFVKITPDRCLIFPSVEFVRNMVLKLGSKSTLP--VVIDCTYIYAADFTAAKVISS 593
             :.:..:|...| :.|...|.||::|.:|..:|....:.:.|  :|::||::.:.|:|....:..
Human   562 -ETKVSEGPVLV-LQPASGLSFPAMEALREEILSRALEVSPPRCLVLECTHVCSIDYTVVLGLGE 624

  Fly   594 IVDDFRRRQQKIIFFNLKPSVVSV 617
            ::.||:::...:.|..|:..|:.|
Human   625 LLQDFQKQGVALAFVGLQVPVLRV 648

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9702	NP_001263113.1	SUL1	72..614	CDD:223732	206/572 (36%)
CG9702	NP_001263113.1	STAS_SulP_like_sulfate_transporter	531..619	CDD:132913	21/89 (24%)
SLC26A11	XP_016879994.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141504
Domainoid	1	1.000	43	1.000	Domainoid score	I12371
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55446
OrthoDB	1	1.010	-	-		D289441at2759
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	1	1.100	-	-	O	PTHR11814
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.720