DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9702 and Slc26a11

DIOPT Version :9

Sequence 1:	NP_001263113.1	Gene:	CG9702 / 43634	FlyBaseID:	FBgn0039787	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	XP_006533481.1	Gene:	Slc26a11 / 268512	MGIID:	2444589	Length:	610	Species:	Mus musculus

Alignment Length:	589	Identity:	209/589 - (35%)
Similarity:	326/589 - (55%)	Gaps:	48/589 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 SKSKSLEQLEASKESKNPESCCSRYARNIFRKKTLLKRLPFLTWLPHYNRQDCIGDLIAGFTVGL 104
            |..|.|.|..:......|::||.       ....|.:|||.|.|:|.|:.|....|.|||.:|||
Mouse     3 SSVKGLGQTRSPSLHMAPDTCCC-------SATALRRRLPVLAWVPDYSLQWLRLDFIAGLSVGL 60

  Fly   105 TVIPQGLAYSGVVGLPPEYGLYGSFMGCFVYVLLGTCKDSTIGSTAVASLMT--FQFAQGSWQRS 167
            |||||.|||:.|.||||:||||.:|||||||..|||.:|.|:|.||:.||:.  :.|.:.::  :
Mouse    61 TVIPQALAYAEVAGLPPQYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFREPAY--A 123

  Fly   168 VLLTFLTGIIEILMAIFKLGCLVEFVSGPVSAGFTSAVALIVSTSQMRSMLGVKSDGGSFLATWI 232
            |||.||:|.|::.|.:..||.|::|:|.||..|||||.::.:...|::::||::.....|.....
Mouse   124 VLLAFLSGCIQLAMGLLHLGFLLDFISCPVIKGFTSAASITIGFGQIKNLLGLQKIPRQFFLQVY 188

  Fly   233 SMFRDIENVRVADTCLGFGCVILLLAMRSLGKFTIGPKDESRRNGFQRVVNTVIKF-------LS 290
            ..|..|...||.|..||...::|||.::.:.:....|..|         :...:||       ::
Mouse   189 HTFLHIGETRVGDAVLGLASMLLLLVLKCMREHMPPPHPE---------MPLAVKFSRGLVWTVT 244

  Fly   291 TSRNASVVILFTAVTMYLDANGTNPFRLTGNIPKGMPTPSLPPFSIEPQPGNETAGIPAVEGQTF 355
            |:|||.||.....:....:..|::||.|||.|.:|:|...:||||:...  |:|.        :|
Mouse   245 TARNALVVSSAALIAYAFEVTGSHPFVLTGKIAEGLPPVRIPPFSVTRD--NKTI--------SF 299

  Fly   356 PEMVQSLGYGLVIVPLMALLETMSVCKAFA--KGKQIDITQEMIACGVGNIATSLFSGYRCNGGL 418
            .||||.:|.||.:||||.|||:::|.|:||  ...:||..||::|.|:.|:..||.|.|...|..
Mouse   300 SEMVQDMGAGLAVVPLMGLLESIAVAKSFASQNNYRIDANQELLAIGLTNVLGSLVSSYPVTGSF 364

  Fly   419 ARSAVNNASGCRTNMSNLYIGVIVVLALNFLTEYIAFIPKAVLAAIIISAVIFQVQYQVVTPMWR 483
            .|:|||..:|..|....|..|.:|:|:||:||...::|||:.|||:||:||......::...:||
Mouse   365 GRTAVNAQTGVCTPAGGLVTGALVLLSLNYLTSLFSYIPKSALAAVIITAVTPLFDVKIFRSLWR 429

  Fly   484 SKRSDLVPGILAFVTCLVLPLEIGIMVAIGVNLLFILYYAARPKVTLEQLETQQGIRFVKITPDR 548
            .:|.||:|..:.|:... ..::.||:....|:||.:|:..||||.     :..:|..|| :.|..
Mouse   430 VQRLDLLPLCVTFLLSF-WEIQYGILAGSLVSLLILLHSVARPKT-----QVSEGQIFV-LQPAS 487

  Fly   549 CLIFPSVEFVRNMVLKLGSKSTLP--VVIDCTYIYAADFTAAKVISSIVDDFRRRQQKIIFFNLK 611
            .|.||:::.:|..:.....:::.|  .|::||:|.:.|:|....:..:::||:::...:.|..|:
Mouse   488 GLYFPAIDALREAITNRALEASPPRSAVLECTHISSVDYTVIVGLGELLEDFQKKGVALAFVGLQ 552

  Fly   612 PSVV 615
            ..|:
Mouse   553 VPVL 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9702	NP_001263113.1	SUL1	72..614	CDD:223732	201/554 (36%)
CG9702	NP_001263113.1	STAS_SulP_like_sulfate_transporter	531..619	CDD:132913	20/87 (23%)
Slc26a11	XP_006533481.1	sulP	35..559	CDD:273284	199/550 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831458
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55446
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	1	1.000	-	-		otm43049
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	1	1.100	-	-	O	PTHR11814
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.710