DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9702 and Slc26a8

DIOPT Version :9

Sequence 1:	NP_001263113.1	Gene:	CG9702 / 43634	FlyBaseID:	FBgn0039787	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	XP_011244686.1	Gene:	Slc26a8 / 224661	MGIID:	2385046	Length:	1027	Species:	Mus musculus

Alignment Length:	702	Identity:	156/702 - (22%)
Similarity:	283/702 - (40%)	Gaps:	168/702 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 PESCCS--RYARNIFRKKTLLKRLPFLTWLPHYNRQD-CIGDLIAGFTVGLTVIPQGLAYSGVVG 118
            ||:.||  ::.|      .:|...|||.|:..|..:| .:|||:||.:|||..:||||..|.:..
Mouse    86 PETSCSWHKFLR------CMLTVFPFLEWICLYRFKDWLLGDLLAGLSVGLVQVPQGLILSLLTR 144

  Fly   119 --LPPEYGLYGSFMGCFVYVLLGTCKDSTIGSTAVASLMTFQ------FAQG------------- 162
              :||....|.:|....:||:.|:|...:||...:.|.:...      |..|
Mouse   145 QLIPPLNVTYAAFCSSVIYVIFGSCHQMSIGPFFLVSALMINVLKDRPFNNGHLILGTFVKDDFS 209

  Fly   163 ------SWQRSVLL----TFLTGIIEILMAIFKLGCLVEFVSGPVSAGFTSAVALIVSTSQMRSM 217
                  |:.||:.:    |||||||::.|.:..:|.:..::....::.:.:||||.:..:||..:
Mouse   210 VPTFYLSYNRSLSMVASTTFLTGIIQLSMGMLGMGFMATYLPEAATSAYLAAVALHIILAQMTCI 274

  Fly   218 LGVKSDGGSFLATWISMFRDIENVRVADTCLGFGCVIL----LLAMRSLGKFTIGPKDESRRNGF 278
            ||:..   ||.|..||...:|.|..:|........::|    ::|:|
Mouse   275 LGIMV---SFHAGPISFIYNIINYCIALPKANSTSILLFITSVVALR------------------ 318

  Fly   279 QRVVNTVIKF------LSTSRNASVVILFTAVTMYLDANGTNPFRLTGNIPKGMPTPSLPPFSIE 337
               :|..|:.      :.......:::.|:.:|..:.....|...|...||.....|..|.|.|
Mouse   319 ---INKCIRITFNRYPIEFPMELLLILGFSLLTSKITMATENSKMLMNMIPYSFVFPENPEFGI- 379

  Fly   338 PQPGNETAGIPAVEGQTFPEMVQSLGYGLVIVPLMALLETMSVCKAF---AKGKQI--------D 391
                                        |..|.|.||  ::|...:|   :.||:|        :
Mouse   380 ----------------------------LSRVVLQAL--SLSFVSSFLLISLGKKIANFHNYRTN 414

  Fly   392 ITQEMIACGVGNIATSLFSGYRCNGGLARSAVNNASGCRTNMSNLYIGVIVVLALNFLTEYIAFI 456
            ..|::||.|:.|:.:|.|......|.|:|:.:.:.||.|...::|....:::|.:..:..:...:
Mouse   415 SNQDLIAIGLCNLLSSFFKCCVFTGSLSRTTIQDKSGGRQQFASLVGAGVMLLLMVKMESFFHNL 479

  Fly   457 PKAVLAAIIISAVI--FQVQYQVVTPMWRSKRSDLVPGILAFVTCLVLPLEIGIMVAIGVNLLFI 519
            |.||||.||:|.|:  .:..|.:.: :||..:.:.:..::.|.:.::|.|::|:::::......|
Mouse   480 PNAVLAGIILSNVVPYLEAIYNLPS-LWRQDQYECIIWMVTFSSAILLGLDVGLLISLAFTFFVI 543

  Fly   520 LYYAARPKV-TLEQLETQQGIRFVKITPDRCLIFPSVEFVRNMVLKLGSKSTLPVVIDC----TY 579
            ...:.|.|: .|.|:....             |:.:|...|.::|..|.|     :..|    |:
Mouse   544 TIRSHRTKILVLGQIPNTN-------------IYRNVNDYREVILIPGVK-----IFQCCSSITF 590

  Fly   580 --IYAADFTAAKVISSIVDDFRRRQQKIIFFNLKPSVVSVFEGLNTRLVLCY-NTHALNQELR-- 639
              :|.......|.::.:....:..:...:|...:.|:.      ..:|..|: :...|..|:|
Mouse   591 VNVYHLKQKVLKEVNMVKLPLKEEEIYTLFHESETSIA------ENKLCRCFCDCEELEPEIRVV 649

  Fly   640 -------PDEPDLSRSVDSLDHAESGNG---TSE-----CVSMASTLSLARS 676
                   ..|.|.|.::....:..||:.   |||     .||..|..::.:|
Mouse   650 YTERYENRQEQDSSINLIRCSYLGSGDSSQVTSEEQIPYTVSSTSQRNIVQS 701

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9702	NP_001263113.1	SUL1	72..614	CDD:223732	133/603 (22%)
CG9702	NP_001263113.1	STAS_SulP_like_sulfate_transporter	531..619	CDD:132913	13/93 (14%)
Slc26a8	XP_011244686.1	sulP	104..610	CDD:273284	131/579 (23%)
Slc26a8	XP_011244686.1	STAS_SulP_like_sulfate_transporter	<747..806	CDD:132913
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289441at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820