Protein Alignment CG9702 and SLC26A3

DIOPT Version :10

• Sequence 1: NP_651810.1
• Gene: CG9702 / 43634
• FlyBaseID: FBgn0039787
• Length: 676
• Species: Drosophila melanogaster
• Sequence 2: NP_000102.1
• Gene: SLC26A3 / 1811
• HGNCID: 3018
• Length: 764
• Species: Homo sapiens
• Alignment Length: 574
• Identity: 142/574 - (24%)
• Similarity: 255/574 - (44%)
• Gaps: 106/574 - (18%)

  Fly    60 CCSRYARNIFRKKTLLKRLPFLTWLPHYNRQD-CIGDLIAGFTVGLTVIPQGLAYSGVVGLPPEY 123
            |||...:.  .|:.:|...|..:|||.|..:: .:.|:::|.:.|:..:.||||::.:|.:||.|
Human    42 CCSCSPQK--AKRIVLSLFPIASWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVY 104

  Fly   124 GLYGSFMGCFVYVLLGTCKDSTIGSTAVASLMTFQFAQGSWQRSV-------------------- 168
            |||.||....:|:..||.:..::|...:.|:|......|:..::|
Human   105 GLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLL 169

  Fly   169 -----------LLTFLTGIIEILMAIFKLGCLVEFVSGPVSAGFTSAVALIVSTSQMRSM--LGV 220
                       .:|.|:|||::...|.::|.:|.::|..:.:|||:|.|:.|..||::.:  |.|
Human   170 DDERVRVAAAASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTV 234

  Fly   221 KS--DGGSFLATWISMFRDIENVRVADTCLGFGCVILLLAMRSLGKFTIGPKDESRRNGFQRVVN 283
            .|  |..|......|:|..||...:||...   .:|:||.:..:       |:.::|...:..|.
Human   235 PSHTDPVSIFKVLYSVFSQIEKTNIADLVT---ALIVLLVVSIV-------KEINQRFKDKLPVP 289

  Fly   284 TVIKFLSTSRNASVVILFTAVTMYLDANGTNPFRLTGNIPKGMPTPSLPPFSIEPQPGNETAGIP 348
            ..|:|:.|       ::...|:...|........:.|::..|...|..|
Human   290 IPIEFIMT-------VIAAGVSYGCDFKNRFKVAVVGDMNPGFQPPITP---------------- 331

  Fly   349 AVEGQTFPEMVQSLGYGLVIVPLMALLETMSVCKAFAKGKQIDITQEMIACGVGNIATSLFSGYR 413
              :.:||...|... :|:.:|.........|| .:......:|..||:||.|:|||...:|.|:.
Human   332 --DVETFQNTVGDC-FGIAMVAFAVAFSVASV-YSLKYDYPLDGNQELIALGLGNIVCGVFRGFA 392

  Fly   414 CNGGLARSAVNNASGCRTNMSNL---YIGVIVVLALNFLTEYIAFIPKAVLAAIIISAVI-FQVQ 474
            .:..|:||||..::|.:|.::.|   .|.:|||||:.||   :|.:.|:||||:.:..:. ..:|
Human   393 GSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIGFL---LAPLQKSVLAALALGNLKGMLMQ 454

  Fly   475 YQVVTPMWRSKRSDLVPGILAFVTCLVLPLEIGIMVAIGVNLLFILYYAARPKV-TLE------- 531
            :..:..:||..:.|.:..|:.|:..:||.|.:|:..::...||.|::....||. ||.
Human   455 FAEIGRLWRKDKYDCLIWIMTFIFTIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNI 519

  Fly   532 --------QLETQQGIRFVKITPDRC---LIFPSVEFVRNMVLKLGSKSTLPVV 574
                    .:...:|::..     ||   :.|.::.|.|..::.....|.|.::
Human   520 YKNKKDYYDMYEPEGVKIF-----RCPSPIYFANIGFFRRKLIDAVGFSPLRIL 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9702	NP_651810.1	SUL1	86..619	CDD:440424	133/548 (24%)
SLC26A3	NP_000102.1	Sulfate_transp	73..475	CDD:459995	112/441 (25%)
		STAS_SulP_like_sulfate_transporter	526..712	CDD:132913	8/48 (17%)
		PDZ-binding. /evidence=ECO:0000269|PubMed:22627094	761..764