DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9702 and Slc26a3

DIOPT Version :9

Sequence 1:	NP_001263113.1	Gene:	CG9702 / 43634	FlyBaseID:	FBgn0039787	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	NP_446207.1	Gene:	Slc26a3 / 114629	RGDID:	620623	Length:	757	Species:	Rattus norvegicus

Alignment Length:	503	Identity:	135/503 - (26%)
Similarity:	237/503 - (47%)	Gaps:	75/503 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 ESCCSRYARNIFRKKTLLKRLPFLTWLPHYN-RQDCIGDLIAGFTVGLTVIPQGLAYSGVVGLPP 121
            :.|||..::.  .||..|...|..:|||.|. ::..:.|:::|.:.||..:.||||::.:|.:||
  Rat    40 KGCCSCSSQK--AKKIALSLFPIASWLPAYKIKEWLLSDIVSGISTGLVAVLQGLAFALLVNIPP 102

  Fly   122 EYGLYGSFMGCFVYVLLGTCKDSTIGSTAVASLM----TFQFAQGSWQRSVL------------- 169
            .||||.:|.....|..|||.:..::|...|.|:|    ..:.|.||.....|
  Rat   103 AYGLYAAFFPVITYFFLGTSRHISVGPFPVLSMMVGVVVTRVASGSDTSPALSSSSAENDSMIEE 167

  Fly   170 -------LTFLTGIIEILMAIFKLGCLVEFVSGPVSAGFTSAVALIVSTSQMRSMLGV----KSD 223
                   :|.|:|||::|:.:.::|.:|.::|..:.:|||:|.|:.|..||::.||.:    .||
  Rat   168 KVMVAASVTVLSGIIQLLLGVLQIGFVVIYLSESLISGFTTAAAIHVLVSQLKFMLQLTVPAHSD 232

  Fly   224 GGSFLATWISMFRDIENVRVADTCLGFGCVILLLAMRSLGKFTIGPKDESRRNGFQRVVNTVIKF 288
            ..|......|:|..|:...:||....   ||:|:.:     |.:  |:.::|...:..|...|:.
  Rat   233 PFSIFKVLESVFSQIQKTNIADLVTS---VIILVVV-----FVV--KEINQRYRSKLPVPIPIEL 287

  Fly   289 LSTSRNASVVILFTAVTMYLDANGTNPFRLTGNIPKGMPTPSLPPFSIEPQPGNETAGIPAVEGQ 353
            :.|       ::.|.::...:........:.||:..|..    ||.:            |:||
  Rat   288 IMT-------VIATGISYGCNFEQRFGVAVVGNMSLGFQ----PPIT------------PSVE-- 327

  Fly   354 TFPEMVQSLGYGLVIVPLMALLETMSVCKAFAKGKQIDITQEMIACGVGNIATSLFSGYRCNGGL 418
            .|.:.:... :|:.||.........|| .:......||..||:||.||.||.|..|.|:..:..|
  Rat   328 VFQDTIGDC-FGIAIVGFAVAFSVASV-YSLKYDYPIDGNQELIALGVSNIFTGAFKGFAGSTAL 390

  Fly   419 ARSAVNNASGCRTNMSNL---YIGVIVVLALNFLTEYIAFIPKAVLAAIIISAVI-FQVQYQVVT 479
            :||.|..::|.:|.::.|   .|.:||::|:.||.:.   :.|:||||:.:..:. ..:|:..:.
  Rat   391 SRSGVQESTGGKTQVAGLLSAVIVLIVIVAIGFLLQP---LQKSVLAALALGNLKGMLMQFAEIG 452

  Fly   480 PMWRSKRSDLVPGILAFVTCLVLPLEIGIMVAIGVNLLFILYYAARPK 527
            .:|:..:.|.:..|:.|:..:||.|.:|:..::...||.|::....||
  Rat   453 RLWKKDKYDCLIWIMTFIFAIVLGLGLGLAASVAFQLLTIVFRTQFPK 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9702	NP_001263113.1	SUL1	72..614	CDD:223732	131/489 (27%)
CG9702	NP_001263113.1	STAS_SulP_like_sulfate_transporter	531..619	CDD:132913
Slc26a3	NP_446207.1	Sulfate_transp	73..468	CDD:395733	114/434 (26%)
Slc26a3	NP_446207.1	STAS_SulP_like_sulfate_transporter	519..705	CDD:132913
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810