DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9702 and slc26a10

DIOPT Version :9

Sequence 1:	NP_001263113.1	Gene:	CG9702 / 43634	FlyBaseID:	FBgn0039787	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	XP_001921766.4	Gene:	slc26a10 / 100150270	ZFINID:	ZDB-GENE-030131-9845	Length:	690	Species:	Danio rerio

Alignment Length:	737	Identity:	176/737 - (23%)
Similarity:	313/737 - (42%)	Gaps:	179/737 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 LITDHRTSKSKSLEQLEASKE---SKNPESC-CSRYARNIFRKKTLLKRLPFLTWLPHYN-RQDC 92
            :.|:.|..::...|.....:|   .:..:.| ||:    :.....|.||||..:|||.|. |:..
Zfish    11 IYTEDRFRQTYGTEDQSGGRERLRDRLAQRCSCSQ----VECVHLLHKRLPVCSWLPKYKLRKWL 71

  Fly    93 IGDLIAGFTVGLTVIPQGLAYSGVVGLPPEYGLYGSFMGCFVYVLLGTCKDSTIGSTAVASLMTF 157
            :||:|||.|||:..||||:|::.:..:.|.||||.||....:|:|.||....:.|:.||.||||.
Zfish    72 LGDIIAGLTVGIVHIPQGMAFALLTSVAPVYGLYTSFFPVVLYMLFGTGHHVSTGTFAVLSLMTG 136

  Fly   158 ------------------QFAQGSWQR---SVLLTFLTGIIEILMAIFKLGCLVEFVSGPVSAGF 201
                              :.|:...||   :..:.||:||:.:.|...:||.|..::|.|:...|
Zfish   137 SVVEQLVPIPLALNSSSPEAAEFEAQRIGVASAVAFLSGIMMLCMCGLQLGFLSTYLSEPIVKAF 201

  Fly   202 TSAVALIVSTSQMRSMLGVK----SDGGSFLATWISMFRDIENVRVADTCLGFGCVILLLAMRSL 262
            |||.|..|:.||::||||::    :...|...|..|:..::.:..:|:..:...|:.:|:.::.:
Zfish   202 TSAAAFHVTVSQLQSMLGLRLPRYAGAFSLFKTLASVMENVPHTNLAELVISLLCLAVLVPVKEV 266

  Fly   263 GKFTIGPKDESRRNGFQRVVNTVIKFLSTSRNASVVILFTAVTMYLDANGTNPFRLTGNIPKGMP 327
                     .||   |:..:.|.|..     ....||:.|.:|.....:.....::.|:||.|.|
Zfish   267 ---------NSR---FRERLRTPIPV-----EIITVIIATGITYAFSLDSKYDIQIVGHIPAGFP 314

  Fly   328 TPSLPPFSIEPQPGNETAGIPAVEGQTFPEMVQSLGYGLVIVPLMALLETMSVCKAFA--KGKQI 390
            .|.||..        ||  :|.:.|.|            |.:.|:|...::|:...:|  .|..|
Zfish   315 EPRLPAL--------ET--VPEIAGDT------------VAITLVAYAVSVSLAMIYADKHGYSI 357

  Fly   391 DITQEMIACGVGNIATSLFSGYRCNGGLARSAVNNASGCRTNMSNLYIGVIVVLALNFLTEYIAF 455
            |..||::|.|:.|..:|||:.:..:..||.:.:..::|..|.::.|:..::|::.|..:.....|
Zfish   358 DPNQELLAHGISNTVSSLFTCFPNSATLATTNILESAGGHTQLAGLFTSLVVLIVLLLIGPLFYF 422

  Fly   456 IPKAVLAAIIISAV--IFQVQYQVVTPMWRSKRSDLVPGILAFVTCLVLPLEIGIMVAI------ 512
            :||||||.|.::::  :| :|:|.:..:||..:.|.:..::.:::.:||.:::|:.:.:
Zfish   423 LPKAVLACINVTSLRQMF-LQFQDLPELWRISKIDFMVWLVTWLSVVVLNVDLGLAIGMVFSMMT 486

  Fly   513 -----------------------------------GVNLLFI---LYYAARP--KVTLEQLETQQ 537
                                               ||.:|..   :||..|.  |..:.||
Zfish   487 VVCRTQRASCSVLGRAANTEIYRSINNHNKCYEVPGVKILTYNGPIYYGNRSFFKADMAQL---- 547

  Fly   538 GIRFVKITPDRCLIFPSVEFVRNMVLK---------------------LGSKSTL---------- 571
                :.:||:|..       .|...||                     ..||:.|
Zfish   548 ----LGLTPERIR-------SREKALKAIEKREREAISTVEQGVADSSFSSKNDLFTSEMAEGEV 601

  Fly   572 -PVVIDCTYIYAADFTAAKVISSIVDDFRRRQQKIIFFNLKPSVVSVF--EGLNTRL------VL 627
             .|:|||:.:...|...|::...:..:.::...:|...|...||:.:.  .||...:      |.
Zfish   602 QAVLIDCSSVIFVDIAGARLFIQMCMECQKIGVRIYLANCNESVLKILTSSGLMNYMNPQHIFVT 666

  Fly   628 CYNTHALNQELRPDEPDLSRSV 649
            .::.....|:.|...|:.:..|
Zfish   667 IHDAVVYIQQQREKPPETNTMV 688

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9702	NP_001263113.1	SUL1	72..614	CDD:223732	160/649 (25%)
CG9702	NP_001263113.1	STAS_SulP_like_sulfate_transporter	531..619	CDD:132913	21/121 (17%)
slc26a10	XP_001921766.4	Sulfate_transp	57..670	CDD:332851	161/667 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.810