DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9702 and slc26a6

DIOPT Version :9

Sequence 1:	NP_001263113.1	Gene:	CG9702 / 43634	FlyBaseID:	FBgn0039787	Length:	676	Species:	Drosophila melanogaster
Sequence 2:	XP_001344243.4	Gene:	slc26a6 / 100005108	ZFINID:	ZDB-GENE-081105-83	Length:	747	Species:	Danio rerio

Alignment Length:	692	Identity:	164/692 - (23%)
Similarity:	288/692 - (41%)	Gaps:	163/692 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSTLENEVTFRKQAEVNQNLEAQFDSSSTDFILITDHRTSKSKSLEQLEASKESKNPESCCSRYA 65
            |..|...|.:..|.||...|.....:..:||               .:...::.|:...|....|
Zfish     5 MKELRKRVPYHIQREVLDELSVDQVAEKSDF---------------NISVKEKLKDAVRCTGPKA 54

  Fly    66 RNIFRKKTLLKRLPFLTWLPHYN-RQDCIGDLIAGFTVGLTVIPQGLAYSGVVGLPPEYGLYGSF 129
            ::.|     |..:|.|.|||.|. |::.|||||:|.:||:..:|||:||:.:..:||.:|||.||
Zfish    55 KSCF-----LSFIPLLAWLPKYPFRENAIGDLISGISVGIMHLPQGMAYALLAAVPPVFGLYSSF 114

  Fly   130 MGCFVYVLLGTCKDSTIGSTAVASLM--------------TF----------QFAQGSWQR---S 167
            ....:|.:.||.|..::|:.||.|:|              ||          .|:....:|   :
Zfish   115 YPILIYFIFGTSKHISVGTYAVMSVMIGSVTERLAPDSDFTFPGNETNSTYIDFSSRDAERVKIA 179

  Fly   168 VLLTFLTGIIEILMAIFKLGCLVEFVSGPVSAGFTSAVALIVSTSQMRSMLGVK----SDGGSFL 228
            ..:|||:||.::|:.:.:.|.:|.::|.|:...:|:|.|:.|..||::...|:.    |...|.:
Zfish   180 ATVTFLSGIFQLLLGVVRFGFVVTYLSEPLVRSYTTAAAIHVIVSQLKYSFGINPHRYSGPLSLI 244

  Fly   229 ATWISMFRDIENVRVADTCLGFGCVILLLAMRSLGKFTIGPKDESRRNGFQRVVNTVI-KFLSTS 292
            .|.|.:                 |.:       |||..||....|    ...:|..:| |.||..
Zfish   245 YTVIEI-----------------CAL-------LGKTNIGTLVVS----IVTIVGLIIAKELSAL 281

  Fly   293 RNASV----------VILFTAVTMYLDANGTNPFRLTGNIPKGMPTPSLPPFSIEPQPGNETAGI 347
            ....:          :|:.|.|:.|:|........:.|.||.|:..|..|..|   |.|
Zfish   282 AAKKIPIPIPVELITIIIATVVSWYMDLKTIYKVEVVGEIPSGLQAPVAPKVS---QLG------ 337

  Fly   348 PAVEGQTFPEMVQSLGYGLVIVPLMALLETMSVCKAFA--KGKQIDITQEMIACGVGNIATSLFS 410
             ::.|..|...|  :|||:.|          |:.:.||  ...::|..||:||.|:.|....|||
Zfish   338 -SMVGDAFALAV--VGYGIAI----------SLGRIFALKYAYKVDSNQELIALGLSNSIGGLFS 389

  Fly   411 GYRCNGGLARSAVNNASGCRTNMSNLYIGVIVVLALNFLTEYIAFIPKAVLAAII-ISAVIFQVQ 474
            .:..:..::||.|..::|.::.::.....:::::.|..:.|....:||||||||| ::......|
Zfish   390 CFAISCSMSRSMVQVSTGGKSQVAGAISALVILVILLKIGELFEELPKAVLAAIIYVNLQGMMKQ 454

  Fly   475 YQVVTPMWRSKRSDLVPGILAFVTCLVLPLEIGIMVAIGVNLLFILYYAARPKVTLEQLETQQGI 539
            :..:..:||:.:.|:|..::..:..::...::|:..:|..::|.:::....||.::
Zfish   455 FGDICSLWRTNKVDMVVWVMTMILTILFNPDMGLAASIAFSILTVVFRTQLPKYSI--------- 510

  Fly   540 RFVKITPDRCLIFPSVEFVRNMVLKLGSKSTLPVVIDCTYIY--AADFTAAKVISSIVDDFRRRQ 602
                                     ||.       |..|.||  ..|:...|.|..|.  ..|..
Zfish   511 -------------------------LGQ-------IPGTDIYKPVEDYNQVKEIPGIT--IFRSS 541

  Fly   603 QKIIFFNLKPSVVSVFE--GLNTRLVLCYNTHALNQELRPDE 642
            ..:.|.|.:..:.:::|  |::...:|.:......:.||.::
Zfish   542 ATLYFANAEMYIDALYEKTGVDVAKLLSHKKKLQAKRLRKEK 583

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9702	NP_001263113.1	SUL1	72..614	CDD:223732	146/589 (25%)
CG9702	NP_001263113.1	STAS_SulP_like_sulfate_transporter	531..619	CDD:132913	13/89 (15%)
slc26a6	XP_001344243.4	sulP	63..729	CDD:273284	150/614 (24%)
slc26a6	XP_001344243.4	STAS_SulP_like_sulfate_transporter	<655..725	CDD:132913
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0659
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000041
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100144
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X49
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.710