Protein Alignment tmod and Lmod1

DIOPT Version :9

• Sequence 1: NP_001247372.1
• Gene: tmod / 43633
• FlyBaseID: FBgn0082582
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_444336.2
• Gene: Lmod1 / 93689
• MGIID: 2135671
• Length: 595
• Species: Mus musculus
• Alignment Length: 550
• Identity: 133/550 - (24%)
• Similarity: 217/550 - (39%)
• Gaps: 162/550 - (29%)

  Fly    91 YGKDLSEYDDVDVESLLAQLSPEEITILAKE---VDPDDNFLPPDQRNSYECTKEATGPLNRKQL 152
            |.:.:||  |.|::|||:.|||||:..|.||   ||||.: :|...|...:..|:.:|..||:.:
Mouse     7 YRRQVSE--DPDIDSLLSTLSPEEMEELEKELDVVDPDGS-IPVGLRQRNQTDKQPSGSFNREAM 68

  Fly   153 I---EHINKQAIETPDQPEFEPFVQGKVRGK----------KWVPPPRDARDI------------ 192
            :   |..:|:.|:.....:....|..|...|          :..|.||...|:
Mouse    69 LNFCEKESKKLIQREMSVDESKQVGRKTDAKNGEEKDSDASRKAPGPRQDSDLGKEPKKGVLKKS 133

  Fly   193 ------EA---------EEQI--AIDMGE-----EYEHALNDATQEEIIDLAAILGFHSMMNQDQ 235
                  ||         ||::  .||.|.     :.:.:..|..:|.    ||     :...:::
Mouse   134 FSRDREEADGRGGEKPKEEKVIRGIDKGRVRAAVDRKESGKDGREER----AA-----AARKEEE 189

  Fly   236 YHASLLNKG-------------QP---------------VGLGWDGITKSTQ------------- 259
            ...|:.|.|             :|               ||...||..|.:.
Mouse   190 KTGSVKNAGLSRDKDKKKEEVKEPSKKEEVKLTAESRNTVGRREDGRLKESSKENKKPEDEGIGS 254

  Fly   260 --------------------------------QKLFPMDPPNNTD-------------VEESIKR 279
                                            :|..|..|...:|             .:|.:::
Mouse   255 GGRDWRKEDEKVKKEENQPDKEVREESKTKAPEKQAPSCPNKPSDGQARAEEEAAPSIFDEPLEK 319

  Fly   280 VKDDDSKLIDLNLNNIKNISDEKLEQLFAALPQNEHLEVLSLTNVGLTDKTALLLAAAIEKSKTL 344
            ||::|.::.::|:||...|::|.|.:...||..|..::|.:|.|....|..|..:|..::.:||:
Mouse   320 VKNNDPEMTEVNVNNSDCITNEILVRFTEALEFNTVVKVFALANTRADDHVAFAIAIMLKANKTI 384

  Fly   345 RVLNVETNFISPPVIVKLVQALLKCHTIEEFRASNQRSAVLGNKIEMEITDLVEKNSSLLRLGLH 409
            ..||:::|.|:...|:.:.:|||:.:|:.|.|..|||. :.|.|.||||..|:::|::||:||.|
Mouse   385 TSLNLDSNHITGKGILAIFRALLQNNTLTELRFHNQRH-ICGGKTEMEIAKLLKENTTLLKLGYH 448

  Fly   410 LEFNDARHRVAAHLQRNIDRIFRVQKLKPNLPKLILPG----NMEIERDLVAYNRSATPSPSPSP 470
            .|....|..|...|.||:|: .|.::|:.........|    .:|:.:.......|..|||.|||
Mouse   449 FELAGPRMTVTNLLSRNMDK-QRQKRLQEQKQAQEASGEKKDRLEVPKVGALAKGSPKPSPQPSP 512

  Fly   471 QPPVDYEVEEDPDNMVIRGGGDAFDPDVDP 500
            :|.        |.|...:.|..|..|...|
Mouse   513 KPA--------PKNSPKKAGVPAAPPPPPP 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tmod	NP_001247372.1	Tropomodulin	91..233	CDD:281268	47/191 (25%)
		LRR_RI	<285..421	CDD:238064	47/135 (35%)
Lmod1	NP_444336.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..69		26/64 (41%)
		Tropomodulin	7..>108	CDD:281268	32/103 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	81..322		33/249 (13%)
		8 X approximate tandem repeats	165..288		13/131 (10%)
		LRR_RI	<315..446	CDD:238064	45/131 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	467..568		18/76 (24%)
		5 X 4 AA approximate tandem repeats	503..522		10/26 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848158
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3735
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10901
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.800