DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tmod and emb2004

DIOPT Version :9

Sequence 1:	NP_001247372.1	Gene:	tmod / 43633	FlyBaseID:	FBgn0082582	Length:	567	Species:	Drosophila melanogaster
Sequence 2:	NP_563871.1	Gene:	emb2004 / 837591	AraportID:	AT1G10510	Length:	605	Species:	Arabidopsis thaliana

Alignment Length:	273	Identity:	62/273 - (22%)
Similarity:	102/273 - (37%)	Gaps:	68/273 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 FVQGKVRGKKWVP--PPRDARDIEAEEQ---------------IAIDMGEEYEHALNDATQE--- 216
            ||..||.||...|  |...|.:..:..|               .|..:..|.:..||:..:|
plant   107 FVLWKVVGKFMSPKSPKTSAGENNSSTQGVKWSIGAGTNLLQGFAAKVDREAKQRLNEFAKELRS 171

  Fly   217 -EIID-------------LAAILGFHSMMNQDQYHASLLNKGQPVGL-GWDGITKSTQQKLFPMD 266
             ..:|             ||..||::..:.:..:.|   |.....|: .:||:.:|...
plant   172 FRSVDMSGCNFGDEGLFFLAESLGYNQTVEEVSFSA---NGITAAGVKAFDGVLQSNIM------ 227

  Fly   267 PPNNTDVEESIKRVKDDDSKLIDLNLNNIKNISDEKLEQLFAALPQNEHLEVLSLTNVGLTDKTA 331
                              .|:::|:.|   .|.||..:.|.|.|.:|..:|:|.|.:..:.|:.|
plant   228 ------------------LKILNLSGN---PIGDEGAKTLCATLMENSSIEILQLNSTDIGDEGA 271

  Fly   332 LLLAAAIEKSKTLRVLNVETNFISPPVIVKLVQALLKCHTIEEFRASNQRSAVLGNKIEMEITDL 396
            ..:|..::::.|||::.:..|.|.......|..|||:.:||.....:......||..   .:...
plant   272 KEIAELLKRNSTLRIIELNNNMIDYSGFTSLAGALLENNTIRNLHLNGNYGGALGAN---ALAKG 333

  Fly   397 VEKNSSLLRLGLH 409
            :|.|.||..|.||
plant   334 LEGNKSLRELHLH 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tmod	NP_001247372.1	Tropomodulin	91..233	CDD:281268	20/94 (21%)
tmod	NP_001247372.1	LRR_RI	<285..421	CDD:238064	36/125 (29%)
emb2004	NP_563871.1	LRR_RI	160..423	CDD:423007	50/220 (23%)
		leucine-rich repeat	173..193	CDD:275380	3/19 (16%)
		leucine-rich repeat	194..221	CDD:275380	6/29 (21%)
		leucine-rich repeat	228..249	CDD:275380	7/23 (30%)
		leucine-rich repeat	250..279	CDD:275380	8/28 (29%)
		leucine-rich repeat	284..311	CDD:275380	8/26 (31%)
		leucine-rich repeat	312..339	CDD:275380	5/29 (17%)
		LRR_RI	315..577	CDD:423007	9/35 (26%)
		leucine-rich repeat	340..368	CDD:275380	4/7 (57%)
		leucine-rich repeat	369..396	CDD:275380
		leucine-rich repeat	425..448	CDD:275380
		leucine-rich repeat	453..480	CDD:275380
		leucine-rich repeat	509..537	CDD:275381
		leucine-rich repeat	538..561	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910