DRSC/TRiP Functional Genomics Resources

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Protein Alignment tmod and ppp1r37

DIOPT Version :9

Sequence 1:NP_001247372.1 Gene:tmod / 43633 FlyBaseID:FBgn0082582 Length:567 Species:Drosophila melanogaster
Sequence 2:NP_001073636.2 Gene:ppp1r37 / 562516 ZFINID:ZDB-GENE-050208-7 Length:919 Species:Danio rerio


Alignment Length:452 Identity:108/452 - (23%)
Similarity:169/452 - (37%) Gaps:139/452 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 DVFGGSA----EETKPEPDAQSKTSVVTEHTEEVIPGETEKMVTETIDEDGDVVEETTEVTRKTV 66
            |...|||    :.|..||.. :|.||.....:    ||.:..|..::||:|.:..|.|..|:   
Zfish    80 DPVNGSAGDLQQSTVEEPPV-TKCSVGDVGDD----GEMDIGVDLSLDENGVLEFEPTAQTQ--- 136

  Fly    67 KRTMKITETSATTKTTTL--TTPAKLYGKDLSEYDDVDVESLLAQLSPEEITILAKEVDPDDNFL 129
                  :|.||::...:|  .|..:|:.::..|...|||.|                        
Zfish   137 ------SEESASSCENSLISDTVIELHSQEPLEEHSVDVPS------------------------ 171

  Fly   130 PPDQRNSYECTKEATGPLNRKQLIEHINKQAIETPDQPEFEPFVQGKVRGKKWVPPPRDARDIEA 194
                    |....|..|:..:..|:|.:|:.    ..|..|..|.|.|..|   .|.|.|:::..
Zfish   172 --------ETVPAAATPVVEEAGIKHGSKRV----TFPSDEDIVSGAVEPK---DPWRHAQNVTV 221

  Fly   195 EEQIAIDMGEEYEHA------------------LNDATQ-EEIIDLAAILGFHSMMNQDQYHASL 240
            ||.:     ..|..|                  |.|.|| .|.:||                   
Zfish   222 EEIL-----NAYRQACQKLNCKPIPKVLKQTQDLKDLTQRNECLDL------------------- 262

  Fly   241 LNKGQPVGL----GWDGITKSTQQKLFPMDPPNNTDVEESIKRVKDDDSKLID----------LN 291
              ||:.:..    ..:.|.|..|.||..::   .|:::|      |..|.|.|          ||
Zfish   263 --KGEKLDYKSCESLEEIFKRVQFKLVDLE---QTNLDE------DGASALFDMIEYYESATHLN 316

  Fly   292 LNNIKNISDEKLEQLFAALPQNEHLEVLSLTNVGLTDKTALLLAAAIEKSKTLRVLNVETNFISP 356
            ::|.|:|.....:.....:.:...|:.|...|..|.|.:|..:|.|:..|.:|.||::|.:.||.
Zfish   317 ISNNKHIGTRGWQAAAHMMRKTNSLQYLDARNTPLLDHSAPFVARALRISSSLTVLHLENSGISG 381

  Fly   357 PVIVKLVQAL-LKCHTIEEFRASN-----QRSAVLGNKIE----MEITDLVEKNSSLLRLGL 408
            ..::.|..|| :..:..|.:.|.|     |.||.|||.::    ::|.||  :|:.:|..||
Zfish   382 RPLMLLATALKMNMNLRELYLAENKLNGLQDSAQLGNLLKFNYNIQILDL--RNNHILDSGL 441

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tmodNP_001247372.1 Tropomodulin 91..233 CDD:281268 31/160 (19%)
LRR_RI <285..421 CDD:238064 42/144 (29%)
ppp1r37NP_001073636.2 LRR_RI 259..577 CDD:238064 54/215 (25%)
leucine-rich repeat 289..311 CDD:275380 6/30 (20%)
leucine-rich repeat 312..340 CDD:275380 5/27 (19%)
LRR 1 340..361 6/20 (30%)
leucine-rich repeat 341..368 CDD:275380 9/26 (35%)
LRR 2 368..388 6/19 (32%)
leucine-rich repeat 369..396 CDD:275380 9/26 (35%)
LRR 3 396..417 6/20 (30%)
leucine-rich repeat 397..425 CDD:275380 9/27 (33%)
LRR 4 425..445 7/19 (37%)
leucine-rich repeat 426..450 CDD:275380 7/18 (39%)
LRR 5 454..474
leucine-rich repeat 455..482 CDD:275380
LRR 6 482..502
leucine-rich repeat 483..510 CDD:275380
leucine-rich repeat 511..538 CDD:275380
leucine-rich repeat 539..558 CDD:275380
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 626..716
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 790..866
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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