DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tmod and lrrc34

DIOPT Version :9

Sequence 1:	NP_001247372.1	Gene:	tmod / 43633	FlyBaseID:	FBgn0082582	Length:	567	Species:	Drosophila melanogaster
Sequence 2:	NP_001373409.1	Gene:	lrrc34 / 556175	ZFINID:	ZDB-GENE-091118-73	Length:	410	Species:	Danio rerio

Alignment Length:	197	Identity:	45/197 - (22%)
Similarity:	77/197 - (39%)	Gaps:	52/197 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   212 DATQEEIIDLAAILGFHSMMNQDQYHASLL-----NKGQPVGLGWDGITKSTQQKLFPMDPPNNT 271
            |...|..:.:.|.|       |...|||:|     ||.....|           ||...|.|.
Zfish     2 DDLMERYLSVCAEL-------QQPTHASVLEVLGNNKSSDCCL-----------KLAGNDQPG-- 46

  Fly   272 DVEESIKRVKDDDSKLIDLNLNNIKNISDEKLEQLFAALPQNEHLEVLSLTNVGLTDKTALLLAA 336
                  .|:.|||..::...|..                  |..::.|.|....:|||.|:.:|.
Zfish    47 ------ARLTDDDMLVLTKTLEG------------------NSAIKGLDLRYNCITDKGAVHIAH 87

  Fly   337 AIEKSKTLRVLNVETNFISPPVIVKLVQALLKCHTIEEFRASNQRSAVLGNKIEMEITDLVEKNS 401
            .|:.||:|:.|::..|.|.......:.::|.|..|::..|.:..:   :||:..|::..:::.|:
Zfish    88 LIQDSKSLQSLDLMCNDIEADGAEVIAKSLHKNITLKTLRMTGNK---IGNQGAMQLATMLQINA 149

  Fly   402 SL 403
            :|
Zfish   150 TL 151

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tmod	NP_001247372.1	Tropomodulin	91..233	CDD:281268	4/20 (20%)
tmod	NP_001247372.1	LRR_RI	<285..421	CDD:238064	25/119 (21%)
lrrc34	NP_001373409.1	RNA1	<21..>138	CDD:227563	36/156 (23%)
		leucine-rich repeat	67..94	CDD:275381	9/26 (35%)
		LRR_RI	<95..332	CDD:423007	13/60 (22%)
		leucine-rich repeat	95..122	CDD:275380	6/26 (23%)
		leucine-rich repeat	123..150	CDD:275380	5/29 (17%)
		leucine-rich repeat	151..178	CDD:275380	1/1 (100%)
		leucine-rich repeat	179..202	CDD:275380
		leucine-rich repeat	210..237	CDD:275380
		leucine-rich repeat	238..265	CDD:275380
		leucine-rich repeat	266..292	CDD:275380
		leucine-rich repeat	323..344	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910