DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tmod and tmod4

DIOPT Version :9

Sequence 1:	NP_001247372.1	Gene:	tmod / 43633	FlyBaseID:	FBgn0082582	Length:	567	Species:	Drosophila melanogaster
Sequence 2:	NP_001016737.1	Gene:	tmod4 / 549491	XenbaseID:	XB-GENE-5884940	Length:	346	Species:	Xenopus tropicalis

Alignment Length:	353	Identity:	125/353 - (35%)
Similarity:	210/353 - (59%)	Gaps:	19/353 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 YGKDLSEYDDVDVESLLAQLSPEEITIL---AKEVDPDDNFLPPDQRNSYECTKEATGPLNRKQL 152
            |.|:|.:|.|:|.:.|:..:||||:..|   .:|:||::..||...|...:.||..||||:|..|
Frog     3 YQKELEKYRDIDEDELMKAMSPEELAQLDFELQEMDPENVLLPAGMRQKDQTTKNPTGPLDRDAL 67

  Fly   153 IEHINKQAIETPDQPEFEPFVQGKVRGKKWVPPPRDARDIEAEEQIAIDMGEEYEHALNDATQEE 217
            :.|:.|:|||..::.:..||. |:.:||.:| |.:..|:|..||||.::  .|.|.||.:||..|
Frog    68 LHHLEKEAIEYKERDDLVPFT-GEKKGKVFV-PKQAKREIPKEEQITLE--PELEEALANATDAE 128

  Fly   218 IIDLAAILGFHSMMNQDQYHAS-----LLNKGQPVGLGWDGITKSTQQKLFPMDPPNNTDVEESI 277
            :.|:|||||.:::|:..||:.:     :.||.     |.:.:.|....|..|.:|||.|:|||::
Frog   129 MCDIAAILGMYTLMSNKQYYDAITTGIITNKE-----GINSVVKPDSYKPVPDEPPNPTNVEETL 188

  Fly   278 KRVKDDDSKLIDLNLNNIKNISDEKLEQLFAALPQNEHLEVLSLTNVGLTDKTALLLAAAIEKSK 342
            |:::.:.|.|.::||||||:|....|:::..|:..|.|:::|||......|..|..:|..::::|
Frog   189 KKIQSNASDLEEVNLNNIKDIPVPTLKEICQAMKSNSHVKILSLVATRSNDPVAYAVAEMLKENK 253

  Fly   343 TLRVLNVETNFISPPVIVKLVQALLKCHTIEEFRASNQRSAVLGNKIEMEITDLVEKNSSLLRLG 407
            ||:.||:|:|||:...::.::||:...:.:.|.:..|||.. ||:.:|||:..::|...|::|.|
Frog   254 TLQSLNIESNFITSAGMLAILQAMRSNNMLSELKVDNQRQN-LGDTVEMEMASMLENCPSIIRFG 317

  Fly   408 LHLEFNDARHRVAAHLQRNIDRIFRVQK 435
            .|......|.|.|..:.:|:: :.|.||
Frog   318 YHFTRQGPRARAATAITKNLE-LRRKQK 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tmod	NP_001247372.1	Tropomodulin	91..233	CDD:281268	58/144 (40%)
tmod	NP_001247372.1	LRR_RI	<285..421	CDD:238064	46/135 (34%)
tmod4	NP_001016737.1	Tropomodulin	3..144	CDD:397382	58/144 (40%)
tmod4	NP_001016737.1	LRR_RI	<185..>281	CDD:423007	33/95 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	132	1.000	Domainoid score	I5059
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I3440
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1025132at2759
OrthoFinder	1	1.000	-	-		FOG0001180
OrthoInspector	1	1.000	-	-		otm47659
Panther	1	1.100	-	-	O	PTHR10901
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X804
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.160