Protein Alignment tmod and TMOD2

DIOPT Version :9

• Sequence 1: NP_001247372.1
• Gene: tmod / 43633
• FlyBaseID: FBgn0082582
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_055363.1
• Gene: TMOD2 / 29767
• HGNCID: 11872
• Length: 351
• Species: Homo sapiens
• Alignment Length: 347
• Identity: 122/347 - (35%)
• Similarity: 196/347 - (56%)
• Gaps: 17/347 - (4%)

  Fly    91 YGKDLSEYDDVDVESLLAQLSPEEITILAK---EVDPDDNFLPPDQRNSYECTKEATGPLNRKQL 152
            :.|:|.:|.::|.:.||.:||.||:..|..   ::||:...||...|...:..|.||||.:|:.|
Human     5 FQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHL 69

  Fly   153 IEHINKQAIETPDQPEFEPFVQGKVRGKKWVPPPRDARDIEAEEQIAIDMGEEYEHALNDATQEE 217
            :.::.|:|:|..|:.:|.||. |:.:|:.::|..:.. :...||::.:|  .|.|.||..|:..|
Human    70 LMYLEKEALEQKDREDFVPFT-GEKKGRVFIPKEKPI-ETRKEEKVTLD--PELEEALASASDTE 130

  Fly   218 IIDLAAILGFHSMMNQDQYHASLLN----KGQPVGLGWDGITKSTQQKLFPMDPPNNTDVEESIK 278
            :.||||:||.|:::|..::.....|    || ||    ..:.|..:.|....:|||.|:||.|::
Human   131 LYDLAAVLGVHNLLNNPKFDEETANNKGGKG-PV----RNVVKGEKVKPVFEEPPNPTNVEISLQ 190

  Fly   279 RVKDDDSKLIDLNLNNIKNISDEKLEQLFAALPQNEHLEVLSLTNVGLTDKTALLLAAAIEKSKT 343
            ::|.:|..|.::||||||||....|.:...||..|.|::..||......|..|:..|..::.:||
Human   191 QMKANDPSLQEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSNDPVAIAFADMLKVNKT 255

  Fly   344 LRVLNVETNFISPPVIVKLVQALLKCHTIEEFRASNQRSAVLGNKIEMEITDLVEKNSSLLRLGL 408
            |..||:|:|||:...|:.||:||.:..|:.|.:..|||.. ||..:||||..::|:||.:|:.|.
Human   256 LTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQ-LGTAVEMEIAQMLEENSRILKFGY 319

  Fly   409 HLEFNDARHRVAAHLQRNIDRI 430
            .......|.||||.:.:|.|.:
Human   320 QFTKQGPRTRVAAAITKNNDLV 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tmod	NP_001247372.1	Tropomodulin	91..233	CDD:281268	49/144 (34%)
		LRR_RI	<285..421	CDD:238064	52/135 (39%)
TMOD2	NP_055363.1	Tropomodulin	5..146	CDD:397382	49/144 (34%)
		LRR_RI	<215..323	CDD:423007	40/108 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157769
Domainoid	1	1.000	134	1.000	Domainoid score	I5012
eggNOG	1	0.900	-	-		E1_KOG3735
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	225	1.000	Inparanoid score	I3507
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47963
OrthoDB	1	1.010	-	-		D1025132at2759
OrthoFinder	1	1.000	-	-		FOG0001180
OrthoInspector	1	1.000	-	-		otm40482
orthoMCL	1	0.900	-	-		OOG6_105629
Panther	1	1.100	-	-	LDO	PTHR10901
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2851
SonicParanoid	1	1.000	-	-		X804
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	14	13.840