Protein Alignment tmod and TMOD3

DIOPT Version :9

• Sequence 1: NP_001247372.1
• Gene: tmod / 43633
• FlyBaseID: FBgn0082582
• Length: 567
• Species: Drosophila melanogaster
• Sequence 2: NP_055362.1
• Gene: TMOD3 / 29766
• HGNCID: 11873
• Length: 352
• Species: Homo sapiens
• Alignment Length: 359
• Identity: 121/359 - (33%)
• Similarity: 198/359 - (55%)
• Gaps: 40/359 - (11%)

  Fly    91 YGKDLSEYDDVDVESLLAQLSPEEI----TILAKEVDPDDNFLPPDQRNSYECTKEATGPLNRKQ 151
            :.|||.:|.|:|.:.||..||..|:    |:| .::||::..||...|...:.:|..|||.:|:.
Human     5 FRKDLEKYKDLDEDELLGNLSETELKQLETVL-DDLDPENALLPAGFRQKNQTSKSTTGPFDREH 68

  Fly   152 LIEHINKQAIETPDQPEFEPFVQGKVRGKKWVPPPRDARDIEAEEQIAIDMGEEYEHALNDATQE 216
            |:.::.|:|:|..|:.::.|:. |:.:||.::|..:..:.. .||::::|  .|.|.||..|:..
Human    69 LLSYLEKEALEHKDREDYVPYT-GEKKGKIFIPKQKPVQTF-TEEKVSLD--PELEEALTSASDT 129

  Fly   217 EIIDLAAILGFHSMMNQ-------------DQYHASLLNKGQPVGLGWDGITKSTQQKLFPM--D 266
            |:.|||||||.|:::..             ||.|.|.:.||               :|:.|:  :
Human   130 ELCDLAAILGMHNLITNTKFCNIMGSSNGVDQEHFSNVVKG---------------EKILPVFDE 179

  Fly   267 PPNNTDVEESIKRVKDDDSKLIDLNLNNIKNISDEKLEQLFAALPQNEHLEVLSLTNVGLTDKTA 331
            |||.|:||||:||.|::|:.|:::||||||||....|:....||..|.|::..||......|..|
Human   180 PPNPTNVEESLKRTKENDAHLVEVNLNNIKNIPIPTLKDFAKALETNTHVKCFSLAATRSNDPVA 244

  Fly   332 LLLAAAIEKSKTLRVLNVETNFISPPVIVKLVQALLKCHTIEEFRASNQRSAVLGNKIEMEITDL 396
            ...|..::.:|||:.||||:|||:...|:.|:.||....|:.|.:..|||.. ||..:|:|:..:
Human   245 TAFAEMLKVNKTLKSLNVESNFITGVGILALIDALRDNETLAELKIDNQRQQ-LGTAVELEMAKM 308

  Fly   397 VEKNSSLLRLGLHLEFNDARHRVAAHLQRNIDRI 430
            :|:|:::|:.|........|.|.|..:.:|.|.:
Human   309 LEENTNILKFGYQFTQQGPRTRAANAITKNNDLV 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tmod	NP_001247372.1	Tropomodulin	91..233	CDD:281268	50/145 (34%)
		LRR_RI	<285..421	CDD:238064	48/135 (36%)
TMOD3	NP_055362.1	Tropomodulin	5..146	CDD:308723	50/145 (34%)
		LRR_RI	<216..>292	CDD:330982	26/75 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	134	1.000	Domainoid score	I5012
eggNOG	1	0.900	-	-		E1_KOG3735
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	225	1.000	Inparanoid score	I3507
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47963
OrthoDB	1	1.010	-	-		D1025132at2759
OrthoFinder	1	1.000	-	-		FOG0001180
OrthoInspector	1	1.000	-	-		otm40482
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10901
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2851
SonicParanoid	1	1.000	-	-		X804
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	12	12.010