DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tmod and lmod2

DIOPT Version :9

Sequence 1:	NP_001247372.1	Gene:	tmod / 43633	FlyBaseID:	FBgn0082582	Length:	567	Species:	Drosophila melanogaster
Sequence 2:	NP_001120284.1	Gene:	lmod2 / 100145340	XenbaseID:	XB-GENE-995983	Length:	549	Species:	Xenopus tropicalis

Alignment Length:	458	Identity:	117/458 - (25%)
Similarity:	207/458 - (45%)	Gaps:	98/458 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 YGKDLSEYDDVDVESLLAQLSPEEITILAKE---VDPDDNFLPPDQRNSYECTKEATGPLNRKQL 152
            |.:::|:|:|:|.:.|||.|:.||:..|.:|   ::|:.| ||...|......|..|...:|:.|
Frog     6 YRREISKYEDIDEDELLASLTAEELQELERELEDIEPNRN-LPVGMRQKSLTEKSPTANFSREAL 69

  Fly   153 IEHINKQA----------------IETPDQPEFEPFV--QGKVRGKKWVPPPRDARDIEAEEQIA 199
            :.:..|:.                .|..|..:.|.||  ..:|..:.:.....:..| |.||::.
Frog    70 MAYWEKETKKLMEKEQLGACDKNYKEEEDGSDEEDFVGTNSEVSEEIYTEEEEEDED-EEEEEVE 133

  Fly   200 IDMGEEYEHALNDATQEEIIDLAAILGF-------HSMMNQDQYHASLLNKGQPVGLGWDGI--- 254
            .:..||      :..|||  |...|.|.       .|..|......:.|:..:.:..|::||
Frog   134 TESDEE------EGNQEE--DKDTICGIADNTEATKSSDNIPTIKINGLSDNKTLSNGYNGIGAK 190

  Fly   255 ------TKSTQQKLFPMDPPNNTDVEESIKRVKDDDSKLIDLNLNNIKNISDEKLEQLFAALPQN 313
                  ..|..:....:...|.|.::::::.:|::|...:::|||||:||:.|.|.....||.:|
Frog   191 YSKQANELSVNKASSGLAGSNPTVIDDALENIKNNDPDTLEVNLNNIENITPETLISFALALKEN 255

  Fly   314 EHLEVLSLTNVGLTDKTALLLAAAIEKSKTLRVLNVETNFISPPVIVKLVQALLKCH-TIEEFRA 377
            .:::|.||.|....|..|:.::..:..::.:..||:|:|||:...|:.:::||...: .:.|.|.
Frog   256 TYVKVFSLANTHADDNVAMAISNMLRVNQNITSLNIESNFITGKGILAIMRALQYSNKVLTELRF 320

  Fly   378 SNQRSAVLGNKIEMEITDLVEKNSSLLRLGLHLEFNDARHRVAAHLQRNID--RIFRVQKLK--- 437
            .|||. ::|:::||||..|::.|:|:::||.|.|....|..:.:.|.||:|  |..|:|:.|
Frog   321 HNQRH-IMGSQVEMEIAKLLKDNTSIIKLGYHFELPGPRMSMTSILTRNMDKQRQRRMQEQKESG 384

  Fly   438 --------------------------------PNLPKLILPGNMEIERDLVAYNRSATPSPSPSP 470
                                            |.:.:.:.|||            ::||||.|.|
Frog   385 YDPTTNLTTKTLQRGTPGASPYSSPRGSPWSSPKITRKVQPGN------------TSTPSPPPPP 437

  Fly   471 QPP 473
            .||
Frog   438 PPP 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tmod	NP_001247372.1	Tropomodulin	91..233	CDD:281268	42/169 (25%)
tmod	NP_001247372.1	LRR_RI	<285..421	CDD:238064	45/136 (33%)
lmod2	NP_001120284.1	Tropomodulin	6..>86	CDD:281268	23/80 (29%)
lmod2	NP_001120284.1	LRR_RI	<218..349	CDD:238064	42/131 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1025132at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10901
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020