DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jdp and DNAJC12

DIOPT Version :9

Sequence 1:	NP_651807.1	Gene:	jdp / 43630	FlyBaseID:	FBgn0027654	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_068572.1	Gene:	DNAJC12 / 56521	HGNCID:	28908	Length:	198	Species:	Homo sapiens

Alignment Length:	211	Identity:	73/211 - (34%)
Similarity:	102/211 - (48%)	Gaps:	32/211 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VDAIINYKRSPNEDFYGLLHCDENSSPEQIQAEYKVLALQYHPDKNSGDKEAEAKFQQLKEAKET 68
            :|||:||:....||:|.||.|||.||.|||.||:||.||:.||||:..:.:|...||:|::|||.
Human     1 MDAILNYRSEDTEDYYTLLGCDELSSVEQILAEFKVRALECHPDKHPENPKAVETFQKLQKAKEI 65

  Fly    69 LCDPEKRAIYDKWRNSGISMSYKQWLGMKEHVGQVRRYTIAEKVDKESMHWVTPKTKDRMLPETG 133
            |.:.|.||.||.||.|.:||.::||..:.:.|             |.|||||....||.||.|:.
Human    66 LTNEESRARYDHWRRSQMSMPFQQWEALNDSV-------------KTSMHWVVRGKKDLMLEESD 117

  Fly   134 ------------GAAAQGPGTGAGCSSGGLTAASPNPAHRRA------SEGGAALYYGSRKGEWG 180
                        ....:........::.......|.|..:..      |.|.|.:.....:..|.
Human   118 KTHTTKMENEECNEQRERKKEELASTAEKTEQKEPKPLEKSVSPQNSDSSGFADVNGWHLRFRWS 182

  Fly   181 GE-NTDVANKFRNYEI 195
            .: .:::..|||||||
Human   183 KDAPSELLRKFRNYEI 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jdp	NP_651807.1	DnaJ	17..79	CDD:278647	33/61 (54%)
DNAJC12	NP_068572.1	CbpA	9..>164	CDD:225124	57/167 (34%)
		DnaJ	14..76	CDD:306689	33/61 (54%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	114..169		4/54 (7%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2214
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8492
Inparanoid	1	1.050	112	1.000	Inparanoid score	I4859
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1499433at2759
OrthoFinder	1	1.000	-	-		FOG0006991
OrthoInspector	1	1.000	-	-		oto89321
orthoMCL	1	0.900	-	-		OOG6_107046
Panther	1	1.100	-	-	LDO	PTHR44500
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4046
SonicParanoid	1	1.000	-	-		X5078
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.860