DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9698 and PH4alphaSG2

DIOPT Version :9

Sequence 1:	NP_651806.2	Gene:	CG9698 / 43629	FlyBaseID:	FBgn0039784	Length:	547	Species:	Drosophila melanogaster
Sequence 2:	NP_651801.1	Gene:	PH4alphaSG2 / 43623	FlyBaseID:	FBgn0039779	Length:	527	Species:	Drosophila melanogaster

Alignment Length:	541	Identity:	167/541 - (30%)
Similarity:	264/541 - (48%)	Gaps:	59/541 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 VSGVEFFSSIHEMTKVFGYEQKMVLHMQKFLSDNQDKLDFLKARLREFENERNEAREWGPS---- 80
            |:..||:||:..|..:...|::::...:.::...|.:|||.:..:.:.:.|    .||..|
  Fly    20 VANGEFYSSVDSMQDLAQVEEELLNATRSYVESQQKQLDFYRRYVEQIKRE----HEWATSQLKL 80

  Fly    81 --YFESPINKYLLNKRLTVDWQRV--ENLMATSTGEKPLTRLRKF---RNRET-MPDKKELEGAI 137
              |...|::.:.|.|||..||..:  |.::|.:..|:    .|.|   .:|:. .||:.||:|||
  Fly    81 DDYLGHPLHAFRLIKRLVRDWDSLIFEPILANNAREE----FRAFVEVLSRDLGYPDQSELQGAI 141

  Fly   138 DGLLRLQYVYRLKAKDLARGILDGVDYGTQLNSEHCVDIARLALRD--QHPRLAHSWLIEANDRL 200
            .||.|||.||.|...|||.||:.|::||:.|....|.:|. :.|.|  ::.| :..||..|...|
  Fly   142 KGLARLQKVYNLATSDLADGIIGGLNYGSDLRWRECYEIG-VQLFDLGEYQR-SLEWLQVAFILL 204

  Fly   201 TGGEKEEQLKPQILALLVQAKKELEDFRGLNDTYQELIGIQSASEEHAKNYETFLNALSEKALLN 265
            ....:||:          .|...|.|.|    .|..:...:..:.:.|..   .|:.:.|....:
  Fly   205 RNSPREEK----------DADHYLSDIR----EYASMANFELGNPKKAAR---LLSQILESQPTH 252

  Fly   266 ESKPILEHAPIPEEGEPVGE-----FQAYSLTCSGHWRLTPKEQR--HLRCGYVTETHPFLWIAP 323
            .::...::......|:.|.|     |..|:..|.|  |..|:|:.  .|||....:.|.:..:||
  Fly   253 SAQQTQKYLESRVPGKNVQETKPSWFSNYTRLCQG--RRLPEERSGDPLRCYLDGKRHAYFTLAP 315

  Fly   324 LKAEELFQDPLLVLYHDVIYQSEI-DVIRKLTENRLMRATIT-SHNESVVSNVRTSQFTFIPVTA 386
            |:.|.:..||.:.:||.::...:| .:..:..:..::|:.:. |..|..|.::|.||.|::...:
  Fly   316 LQVEPVHLDPDINVYHGMLSSKQILSIFEEADKEEMVRSAVAGSGGEGTVRDLRVSQQTWLDYKS 380

  Fly   387 HKVLSTIDQRVADMTNLNMKYAEDHQFANYGIGGHYGQHMDWFYQTTFDAGLVSSPEMGNRIATV 451
             .|::::.:.:..::..:|..||..|.||||:||.|..|.|:     |:..|..:.| |:||:|.
  Fly   381 -PVMNSVGRIIQFVSGFDMAGAEHMQVANYGVGGQYEPHPDY-----FEVNLPKNFE-GDRISTS 438

  Fly   452 LFYLSDVAQGGGTAFPQLRTLLKPKKYAAAFWHNLHASGVGDVRTQHGACPIIAGSKWVQNRWIR 516
            :||||||.|||.|.|.:|...|.|.|.|...|||||.|...|.||.|..||:|.|||.:.|.|:.
  Fly   439 MFYLSDVEQGGYTVFTKLNVFLPPVKGALVMWHNLHRSLHVDARTLHAGCPVIVGSKRIGNIWMH 503

  Fly   517 ENDQSDRRPCELWDDSLATYA 537
            ...|..||||.|..||..:.|
  Fly   504 SGYQEFRRPCNLTSDSYKSLA 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9698	NP_651806.2	P4Ha_N	28..159	CDD:285528	44/142 (31%)
CG9698	NP_651806.2	P4Hc	345..516	CDD:214780	64/172 (37%)
PH4alphaSG2	NP_651801.1	P4Ha_N	28..163	CDD:285528	44/142 (31%)
PH4alphaSG2	NP_651801.1	P4Hc	335..503	CDD:214780	64/174 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461858
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28396
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	11	10.910