DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9698 and CG18234

DIOPT Version :9

Sequence 1:	NP_651806.2	Gene:	CG9698 / 43629	FlyBaseID:	FBgn0039784	Length:	547	Species:	Drosophila melanogaster
Sequence 2:	NP_649043.3	Gene:	CG18234 / 40024	FlyBaseID:	FBgn0265268	Length:	515	Species:	Drosophila melanogaster

Alignment Length:	543	Identity:	153/543 - (28%)
Similarity:	231/543 - (42%)	Gaps:	118/543 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 SIHEMTKVFGYEQKMVLHMQKFLSDNQDKLDFLKARLREFENERNEAREWGPSYFESPINKYLLN 92
            ||..|.::...|...:..|:.:.:..::|:|.:::.|:|.:::|..:|.....:...|:|.:.|.
  Fly    27 SIAGMKELVDLEGFFISEMESYTAALKNKIDLMESLLQEVQSKREISRRNPEEFVAHPLNAFSLI 91

  Fly    93 KRLTVDWQRVENLMATSTGEKPLTRLRKFRN--RETMPDKKELEGAIDGLLRLQYVYRLKAKDLA 155
            :||..||.:.|.||....|   |..|:....  .|..|...:|..||.|::.||..|.|:..|:|
  Fly    92 RRLHEDWTQAELLMLNQVG---LEHLQAIETGLEEAQPSDNDLNDAIGGIISLQQFYNLQPSDIA 153

  Fly   156 RGILDGVDYGTQLNSEHCVDIARLALRDQHPRLAHSWLIEA----NDRLTGGEKEEQLKPQILAL 216
            .|:|.|..|...|.:.:|..:|...:...:.:.|.:|...|    ||...|
  Fly   154 NGLLMGQQYNASLTTLNCQALANACMNFNYDKYALNWFKAAVDHYNDDRDG-------------- 204

  Fly   217 LVQAKKELEDFRGLNDTYQELIGIQSASEEHAKNYETFL----------NALSEKALLNES---- 267
              |..:|:.||| |.|.|              .||.:.|          ..|.:.|.|:.:
  Fly   205 --QVYREVFDFR-LPDLY--------------INYTSVLVTKGFRKAAWKVLQDVADLDATLWLL 252

  Fly   268 -KPILEHAPIPEEGEPVGEFQAYSLTCSGHWRLTP-----------KEQRHLRCGYVTETHPFLW 320
             |.|.|          ||:......|    :.:||           :..:||.|.|...|..||.
  Fly   253 RKDIYE----------VGKIDVPDPT----FIITPWFDVTGCLRVGQTSQHLSCHYEKNTSEFLR 303

  Fly   321 IAPLKAEELFQDPLLVLYHDVIYQSEIDVIRKLTENRL---MRATITSHNESVVSNVRTSQFTFI 382
            |||||.|.|...|.:||||||||.|||..::.::...|   :|...........:.:|..
  Fly   304 IAPLKVETLSLKPHIVLYHDVIYDSEISKVKNISLPSLKSPLRILYAIDYNLKFAKIRED----- 363

  Fly   383 PVTAHKVLSTIDQRVADMTNLNMKYAEDHQFANYGIGGHYGQHMDWFY---QTTFDAGLVSSPEM 444
                |:  |.:..|:.|||..:::...|.|..||||.|....|.|...   ||.         |:
  Fly   364 ----HQ--SPLSLRIKDMTGEDVQEDTDFQIDNYGICGFRNFHTDNIELQDQTA---------EL 413

  Fly   445 GNRIATVLFYLSDVAQGGGTAFPQLRTLLKPKKYAAAFWHNLHASGVGDVRTQ------HGACPI 503
            |:|:.:::|:::||||||..|||.|...:.|:|.:|..|.||      |.|.|      |.:||:
  Fly   414 GDRLTSIMFFMNDVAQGGALAFPNLNLTIWPQKGSALVWRNL------DHRMQPNQDLLHVSCPV 472

  Fly   504 IAGSKWVQNRWIRENDQSDRRPC 526
            :.||||...:|:.|..|...|||
  Fly   473 VVGSKWTLVKWLHERPQMFSRPC 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9698	NP_651806.2	P4Ha_N	28..159	CDD:285528	37/132 (28%)
CG9698	NP_651806.2	P4Hc	345..516	CDD:214780	54/182 (30%)
CG18234	NP_649043.3	P4Ha_N	27..157	CDD:285528	37/132 (28%)
CG18234	NP_649043.3	P4Hc	<371..485	CDD:214780	46/128 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461929
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	9	8.900