DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9698 and p4ha1

DIOPT Version :9

Sequence 1:	NP_651806.2	Gene:	CG9698 / 43629	FlyBaseID:	FBgn0039784	Length:	547	Species:	Drosophila melanogaster
Sequence 2:	XP_031761963.1	Gene:	p4ha1 / 100490484	XenbaseID:	XB-GENE-987760	Length:	526	Species:	Xenopus tropicalis

Alignment Length:	528	Identity:	168/528 - (31%)
Similarity:	269/528 - (50%)	Gaps:	22/528 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 HQAIP-----SVSGVEFFSSIHEMTKVFGYEQKMVLHMQKFLSDNQDKLDFLKARLREFENERNE 73
            |..:|     |.:..:||:||..|..:...|:.:|..::.::...:.||..:|....:.::..:.
Frog     4 HLVLPLLGLFSCAHADFFTSIGHMIDLLNTEKDLVTSLKDYIKAEEQKLAQIKKWADKLDHLTDT 68

  Fly    74 AREWGPSYFESPINKYLLNKRLTVDWQRVENLMATSTGEKPLTRLRKFRNRETMPDKKELEGAID 138
            |.:....|...|:|.:.|.|||..:|.::|||:.....:..::.|.  ..|:..|:.::..||..
Frog    69 ATKDPEGYLGHPVNAFKLMKRLNTEWVKLENLILKDISDGFISNLT--IQRQYFPNDEDQTGAAK 131

  Fly   139 GLLRLQYVYRLKAKDLARGILDGVDYGTQLNSEHCVDIARLALRDQHPRLAHSWLIEANDRLTGG 203
            .|||||..|.|....:::|.|.||.:.|.|.:|.|.|:.:.|..|........|:.:|..:|..|
Frog   132 ALLRLQDTYNLDTDTISKGNLPGVKHKTSLTAEDCFDLGKTAYTDADYYHTELWMEQALSQLDAG 196

  Fly   204 EKEEQLKPQILALLVQAKKELEDF-RGLNDTYQELIGIQSASEEHAKNYETFLNALSEKALLNES 267
            |:....|..:|..|..|..:..|. :.|..|.:.|    ....||.:......:.:|:::..:.|
Frog   197 EESSLDKVMVLDYLSYAVYQQGDLDKALTLTKRSL----ELDPEHQRGNGNLRHIMSKESNKSSS 257

  Fly   268 KPILEHAPI-PEEGEPVG--EFQAYSLTCSGHW-RLTPKEQRHLRCGYVT-ETHPFLWIAPLKAE 327
            .| .|.|.: ..:|.|..  |.:.|...|.|.. ::|.:.|:.|.|.|.. :..|.|.::|.|.|
Frog   258 SP-SEGAELRTRKGRPKDHLEKEKYEKLCRGEGVKMTSRRQKRLFCRYFDGKKDPLLILSPTKQE 321

  Fly   328 ELFQDPLLVLYHDVIYQSEIDVIRKLTENRLMRATITSHNESVV--SNVRTSQFTFIPVTAHKVL 390
            :.:..|.:|.|||:|...||..:::|.:.||.||||::....|:  :..|.::..::......|:
Frog   322 DEWDKPRIVRYHDIISDEEISKVKELAKPRLRRATISNPITGVLETAQYRITKSAWLSGYEDPVV 386

  Fly   391 STIDQRVADMTNLNMKYAEDHQFANYGIGGHYGQHMDWFYQTTFDAGLVSSPEMGNRIATVLFYL 455
            :.:::|:..:|.|:|..||:.|.|||||||.|..|.|:..:...||  ......|||:||.|||:
Frog   387 ARLNRRIEGVTGLDMSTAEELQVANYGIGGQYEPHFDFLRKYEPDA--FKKLGTGNRVATWLFYM 449

  Fly   456 SDVAQGGGTAFPQLRTLLKPKKYAAAFWHNLHASGVGDVRTQHGACPIIAGSKWVQNRWIRENDQ 520
            |||..||.|.||::...:.|||..|.||:||..||.||..|:|.|||::.|:|||.|:||.|..|
Frog   450 SDVEAGGATVFPEVGAAVYPKKGTAVFWYNLLESGEGDYSTRHAACPVLVGNKWVSNKWIHERGQ 514

  Fly   521 SDRRPCEL 528
            ..||||.|
Frog   515 EFRRPCNL 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9698	NP_651806.2	P4Ha_N	28..159	CDD:285528	33/130 (25%)
CG9698	NP_651806.2	P4Hc	345..516	CDD:214780	70/172 (41%)
p4ha1	XP_031761963.1	P4Ha_N	24..111	CDD:400573	19/86 (22%)
p4ha1	XP_031761963.1	P4Hc	337..510	CDD:214780	70/174 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.110