DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaNE2 and AT3G28490

DIOPT Version :9

Sequence 1:	NP_733378.1	Gene:	PH4alphaNE2 / 43628	FlyBaseID:	FBgn0039783	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_189490.2	Gene:	AT3G28490 / 822479	AraportID:	AT3G28490	Length:	288	Species:	Arabidopsis thaliana

Alignment Length:	250	Identity:	67/250 - (26%)
Similarity:	108/250 - (43%)	Gaps:	25/250 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   305 NLYCVYNHVTSPFLQLAPIKTEILSIDPFVVLLHDMISQKE-STLIRTSSKEHMLPSATTDPDAS 368
            :|..:::.::|....:.|.:...||..|...|....:|.:| ..||:.:..:  |..:....|..
plant    12 SLLLIFSQISSFSFSVDPTRITQLSWTPRAFLYKGFLSDEECDHLIKLAKGK--LEKSMVVADVD 74

  Fly   369 DDETQVDTYRTSKSVWYSSDFNDTTKKITERLGDATGLDMNSTEFYQVINYGLGGFFETHLDMLL 433
            ..|::....|||..::.:...:|....:..:|...|.|...:.|..|:::|..|..::.|.|...
plant    75 SGESEDSEVRTSSGMFLTKRQDDIVANVEAKLAAWTFLPEENGEALQILHYENGQKYDPHFDYFY 139

  Fly   434 SEKNRFNGTSDRIATTLFYLNEVRQGGGTYFP------------------RLNLTVFPQPGSALF 480
            .:|....| ..||||.|.||:.|.:||.|.||                  :....|.|:.|.||.
plant   140 DKKALELG-GHRIATVLMYLSNVTKGGETVFPNWKGKTPQLKDDSWSKCAKQGYAVKPRKGDALL 203

  Fly   481 WYNLDTKGNDHMGSLHTGCPVIVGSKWVMSKWIN--DMGQEFTRPCVESSLSSNE 533
            ::||...|.....|||..||||.|.||..::||:  ..|:: ...||:...|..|
plant   204 FFNLHLNGTTDPNSLHGSCPVIEGEKWSATRWIHVRSFGKK-KLVCVDDHESCQE 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE2	NP_733378.1	P4Ha_N	33..161	CDD:285528
		TPR repeat	175..200	CDD:276809
		TPR_16	176..254	CDD:290168
		TPR repeat	219..249	CDD:276809
		TPR_2	220..253	CDD:285020
		P4Hc	342..513	CDD:214780	53/189 (28%)
AT3G28490	NP_189490.2	PLN00052	28..288	CDD:177683	64/233 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.920