DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaNE2 and AT-P4H-1

DIOPT Version :9

Sequence 1:	NP_733378.1	Gene:	PH4alphaNE2 / 43628	FlyBaseID:	FBgn0039783	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_181836.1	Gene:	AT-P4H-1 / 818910	AraportID:	AT2G43080	Length:	283	Species:	Arabidopsis thaliana

Alignment Length:	245	Identity:	60/245 - (24%)
Similarity:	104/245 - (42%)	Gaps:	42/245 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   296 RCQVPRNLSNLYCVYNHVTSPFLQLAPIKTEILSIDPFVVLLHDMISQKESTLIRTSSKEHMLPS 360
            |.|..|.|.::....|...:..|::..:|.|::|..|.:::|||.:|.:|...::..::..:..|
plant    48 RGQNTRYLRDVSRWANDKDAELLRIGNVKPEVVSWSPRIIVLHDFLSPEECEYLKAIARPRLQVS 112

  Fly   361 ATTDPDASDDETQVDTYRTSKSVWYSSDFNDTT--------------KKITERLGDATGLDMNST 411
            ...|            .:|.|.|  .||...::              :.|.:|:...:.:...:.
plant   113 TVVD------------VKTGKGV--KSDVRTSSGMFLTHVERSYPIIQAIEKRIAVFSQVPAENG 163

  Fly   412 EFYQVINYGLGGFFETHLDMLLSEKNRFNGTSDRIATTLFYLNEVRQGGGTYFP----------- 465
            |..||:.|....|::.|.|......|...| ..|:||.|.||.:..:||.||||
plant   164 ELIQVLRYEPQQFYKPHHDYFADTFNLKRG-GQRVATMLMYLTDDVEGGETYFPLAGDGDCTCGG 227

  Fly   466 --RLNLTVFPQPGSALFWYNLDTKGNDHMGSLHTGCPVIVGSKWVMSKWI 513
              ...::|.|..|.|:.::::...|.....|:|.||.|:.|.||..:||:
plant   228 KIMKGISVKPTKGDAVLFWSMGLDGQSDPRSIHGGCEVLSGEKWSATKWM 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE2	NP_733378.1	P4Ha_N	33..161	CDD:285528
		TPR repeat	175..200	CDD:276809
		TPR_16	176..254	CDD:290168
		TPR repeat	219..249	CDD:276809
		TPR_2	220..253	CDD:285020
		P4Hc	342..513	CDD:214780	46/197 (23%)
AT-P4H-1	NP_181836.1	PLN00052	80..281	CDD:177683	52/213 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.920