DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaNE2 and P4H5

DIOPT Version :9

Sequence 1:	NP_733378.1	Gene:	PH4alphaNE2 / 43628	FlyBaseID:	FBgn0039783	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_179363.1	Gene:	P4H5 / 816281	AraportID:	AT2G17720	Length:	291	Species:	Arabidopsis thaliana

Alignment Length:	208	Identity:	61/208 - (29%)
Similarity:	100/208 - (48%)	Gaps:	22/208 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   326 EILSIDPFVVLLHDMISQKESTLIRTSSKEHMLPSATTDPDASDDETQVDTYRTSKSVWYSSDFN 390
            |::|.:|..|:.|:.::.:|...:.:.:|..|:.|...|......:.  ...|||...:.....:
plant    81 EVISWEPRAVVYHNFLTNEECEHLISLAKPSMVKSTVVDEKTGGSKD--SRVRTSSGTFLRRGHD 143

  Fly   391 DTTKKITERLGDATGLDMNSTEFYQVINYGLGGFFETHLDMLLSEKNRFNGTSDRIATTLFYLNE 455
            :..:.|.:|:.|.|.:.:.:.|..||::|.:|..:|.|.|..|.|.|..|| ..||||.|.||::
plant   144 EVVEVIEKRISDFTFIPVENGEGLQVLHYQVGQKYEPHYDYFLDEFNTKNG-GQRIATVLMYLSD 207

  Fly   456 VRQGGGTYFP-------------------RLNLTVFPQPGSALFWYNLDTKGNDHMGSLHTGCPV 501
            |..||.|.||                   :..|:|.|:...||.::|:....:....|||.||||
plant   208 VDDGGETVFPAARGNISAVPWWNELSKCGKEGLSVLPKKRDALLFWNMRPDASLDPSSLHGGCPV 272

  Fly   502 IVGSKWVMSKWIN 514
            :.|:||..:||.:
plant   273 VKGNKWSSTKWFH 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE2	NP_733378.1	P4Ha_N	33..161	CDD:285528
		TPR repeat	175..200	CDD:276809
		TPR_16	176..254	CDD:290168
		TPR repeat	219..249	CDD:276809
		TPR_2	220..253	CDD:285020
		P4Hc	342..513	CDD:214780	55/189 (29%)
P4H5	NP_179363.1	PLN00052	75..290	CDD:177683	61/208 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.920