Protein Alignment PH4alphaNE2 and p4htma

DIOPT Version :10

• Sequence 1: NP_733378.1
• Gene: PH4alphaNE2 / 43628
• FlyBaseID: FBgn0039783
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_001074160.1
• Gene: p4htma / 791209
• ZFINID: ZDB-GENE-070112-2222
• Length: 478
• Species: Danio rerio
• Alignment Length: 321
• Identity: 69/321 - (21%)
• Similarity: 105/321 - (32%)
• Gaps: 124/321 - (38%)

  Fly   318 LQLAPIKT---EILSIDPFVVLLHDMISQKESTLIRTSSKEHML--PSATTDPDASDDETQVDTY 377
            :.:.|.:|   ..||:.|.:..:...:|.:||.::...::...|  .|..|:||..:..||.:.:
Zfish   123 VSIVPDRTHNMRTLSLKPLLFEIPGFLSVEESNVVMQLAQLKGLTHSSLLTNPDQEEQLTQDELF 187

  Fly   378 --------------------RTSKSVWYSS---------------------DFNDTTKKITERLG 401
                                .::...|.||                     :|...:..:....|
Zfish   188 SLLDLNQDGLLQREEILSLSHSTDGSWLSSYNLRKIHTGLETNPSGVLSLQEFKRVSGGVLRYSG 252

  Fly   402 DATGLD-----------------------------------------MNSTEFYQVINYGLGGFF 425
            .|.|||                                         ::.:|..:|:.|..|.|.
Zfish   253 AAQGLDGHTKVRQRSTHTRLYLGEGTHHLLKSVRNRVTRLTRLPSSLVDLSEAMEVVRYEQGVFS 317

  Fly   426 E-------THLDMLLSEKNRFNGTSDRIA----TTLFYLNEVRQGGGTYFP-------------- 465
            .       ||.|...:..:....||:::|    |.|.|||....||.|.||
Zfish   318 HAHHDSSPTHPDNSCTHTHLAANTSNQVACRYLTVLLYLNSADSGGETSFPVADNRTYEEEVLGD 382

  Fly   466 -------RLNLTVFPQPGSALFWYNLDTKGNDHMG-----SLHTGCPVIVGSKWVMSKWIN 514
                   :.||.|.|..|:||.|||..:.||..:|     |||..|.|..|.||..|.|:|
Zfish   383 LSQQYCDKGNLKVKPVAGTALLWYNHLSDGNGWVGELDEFSLHGDCLVTRGFKWTGSVWVN 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE2	NP_733378.1	P4Ha_N	33..163	CDD:462433
		TPR repeat	175..200	CDD:276809
		TPR_16	176..254	CDD:433202
		NrfG	217..>260	CDD:443378
		TPR repeat	219..249	CDD:276809
		P4Hc	342..513	CDD:214780	62/291 (21%)
p4htma	NP_001074160.1	XopAW	169..>240	CDD:469301	9/70 (13%)
		PLN00052	<248..471	CDD:177683	50/196 (26%)