Protein Alignment PH4alphaNE2 and CG31021

DIOPT Version :9

• Sequence 1: NP_733378.1
• Gene: PH4alphaNE2 / 43628
• FlyBaseID: FBgn0039783
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_733392.2
• Gene: CG31021 / 43638
• FlyBaseID: FBgn0051021
• Length: 453
• Species: Drosophila melanogaster
• Alignment Length: 486
• Identity: 133/486 - (27%)
• Similarity: 217/486 - (44%)
• Gaps: 50/486 - (10%)

  Fly    40 MLNLEDDLVSNVEKLAEALARKAKTIKWGVFKMMKRRQEYKSSME--------IFANPIDTFSLI 96
            |||||.:|:.|:...||.|..|...|...|       ::|...:|        ..:||:::|.||
  Fly     1 MLNLERNLLQNMRDYAEKLEEKIDLINNYV-------EDYNVDIEDANEDPEKYLSNPLNSFRLI 58

  Fly    97 RHMQSNWLMWLLYLETPVGQEELFFVDSRMPLLPKYFDFIDAAEGIRKMQATYQMFSSD-IAKGL 160
            |||..:|:.|.:|:|..|..|.:..|:|.:|.||:...|..||..:..:...|....:| :||
  Fly    59 RHMHQDWVGWQVYMEDLVAPEAVQKVESLLPQLPQKEAFRKAARSVHSLTQFYGYEPADLVAK-- 121

  Fly   161 LDGVQYNSSLKPIDCLAIGLHLMNNSRWYAAEQWISASIEAYDQKSSQTDMELLRGPKLADLCRI 225
             |....:..|.|:||..:||.|.....:..|.:|:..:...|.....:.....|..|:. .:.|.
  Fly   122 -DERSSSLHLSPLDCYHLGLELYEEQDYLGAAKWLQVAAHNYTLSRHRDLFNPLGAPRW-QVYRD 184

  Fly   226 LGQVQMKQRNHEGALQAYQVALKLSPHDPEIYEEYRILEKRDLTLSDIEPIEQDKDNSHERLVLP 290
            ||:..:| .|.:.|..||:.||:|:..:..:.:|...:|...|.    :|:|...|...:..||.
  Fly   185 LGRTLLK-LNRQCAYDAYESALRLNSQNVHLMKEAGQMELFSLR----DPMEPILDLQPKPTVLE 244

  Fly   291 PCCSGRCQVPRNLSNLYCVYNHVTSPFLQLAPIKTEILSIDPFVVLLHDMISQKESTLIRTSSKE 355
            ..|.|  :|||:...|.|..|.....||..||||.|.|..|||::|....|.::|...:. ::.|
  Fly   245 KYCRG--EVPRHQGRLTCELNDWVHSFLAYAPIKFEDLQQDPFIILYPGSIYEQEIRHVE-NAYE 306

  Fly   356 HMLPSATTDPDASDDETQVDTYRTSKSVWYSSDFNDTTKKITERLGDATGLDMNSTEFYQVINYG 420
            ...|         :|..::....:..|:  |..::...|:|.||:.|..|::.....|| ::.|.
  Fly   307 RCPP---------NDRFELKLGISGCSI--SDGYSPVLKRINERILDMAGVEKTWDTFY-IVEYA 359

  Fly   421 -LGGF--FETHLDMLLSEKNRFNGTSDRIATTLFYLNEVRQGGGTYFPRLNLTVFPQPGSALFWY 482
             |..|  |:...:.....|.......|..|..:.:|.:|..||....|..::.|.|:.|:.|..:
  Fly   360 QLAPFEPFKLFRNSTKFPKLNLMNFEDVEAKVIIFLKDVTLGGAFTMPNGDILVQPKRGNVLITF 424

  Fly   483 NLDTKGNDHMGSLHTGCPVIVGSKWVMSKWI 513
                :..:|..::   ||:|.|:..||.|:|
  Fly   425 ----ENEEHSTTI---CPIIEGTGLVMIKFI 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE2	NP_733378.1	P4Ha_N	33..161	CDD:285528	41/129 (32%)
		TPR repeat	175..200	CDD:276809	6/24 (25%)
		TPR_16	176..254	CDD:290168	19/77 (25%)
		TPR repeat	219..249	CDD:276809	10/29 (34%)
		TPR_2	220..253	CDD:285020	11/32 (34%)
		P4Hc	342..513	CDD:214780	38/173 (22%)
CG31021	NP_733392.2	P4Ha_N	1..119	CDD:285528	39/124 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452368
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D391515at2759
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.990