Protein Alignment PH4alphaNE2 and CG18233

DIOPT Version :10

• Sequence 1: NP_733378.1
• Gene: PH4alphaNE2 / 43628
• FlyBaseID: FBgn0039783
• Length: 542
• Species: Drosophila melanogaster
• Sequence 2: NP_649044.3
• Gene: CG18233 / 40025
• FlyBaseID: FBgn0036795
• Length: 515
• Species: Drosophila melanogaster
• Alignment Length: 515
• Identity: 146/515 - (28%)
• Similarity: 247/515 - (47%)
• Gaps: 57/515 - (11%)

  Fly    30 FARSVVNMDDMLNLEDDLVSNVEKLAEALARKAKTIKWGVFKMMKRRQEYKSSME---IFANPID 91
            ::.||:.:..:|.:|.:.:.|....|..|..|...:  .:|....:|..:|:..|   ..:||::
  Fly    31 YSSSVLGLVKLLKMEQEFMVNFSIYANILQEKVDNL--NIFLDALKRPNHKTHNEREKFVSNPLN 93

  Fly    92 TFSLIRHMQSNWLMWLLYLETPVGQEELFFVDSRMPLLPKYFDFIDAAEGIRKMQATYQMFSSDI 156
            .|.|||.:..:|.....|.:.|:|.|:|..:...:...|:.||..:..:.:.:::.||.:...||
  Fly    94 AFGLIRRLNQDWPKLQNYTQKPLGLEQLTAMQDIVSAAPESFDMNEKLKAMHRIETTYDLQPKDI 158

  Fly   157 AKGLLDGVQYNSSLKPIDCLAIGLHLMNNSRWYAAEQWISASIEAYDQKSSQTDMELLRGPKLAD 221
            |||||...::|..|...||||:..|......:..:..|...:::.      .||
  Fly   159 AKGLLQRTEFNYRLLFRDCLALAYHKFEIGEFKRSLLWFQEALKL------STD----------- 206

  Fly   222 LCRILGQVQMKQRNHEGALQAYQVAL-KLSPH------DPEIYEEYRILEKRDLTLSDIEPI--E 277
                 |.:::..|..|..|:.:..|: |.|.:      ..|..::....:.:|..|.|:|.:  .
  Fly   207 -----GSLEIMNRLKEIELKGFATAVAKRSIYLSNQGLTNETIDDMANSQLQDAKLMDLEQLISS 266

  Fly   278 QDKDNSHERLVLPPC-----CSGRCQVPRNLSNLYCVYNHVTSPFLQLAPIKTEILSIDPFVVLL 337
            :.|...::....||.     |.|  ..|:. |||.|.||..|:.||:|||:|.|.:|.||::|:.
  Fly   267 ELKQWINDDSTTPPTDHNLGCRG--LFPKK-SNLVCRYNSSTNAFLKLAPLKMEEISRDPYIVMF 328

  Fly   338 HDMISQKESTLIRTSSKEHMLPSATTDPDASDDETQVDTYRTSKSVWYSSDFNDTTKKITERLGD 402
            |::||.|:...::....|  :.:..|   :..|..::    .|:..|...: :..:|:|.:|:.|
  Fly   329 HEVISDKDIEEMKGEITE--MENGWT---SLGDPKEI----VSRVYWIRKE-SSFSKRINQRISD 383

  Fly   403 ATGLDMNSTEFYQVINYGLGGFFETHLDML---LSEKNRFNGTSDRIATTLFYLNEVRQGGGTYF 464
            .||..:......|:.|:|:||:|:.|.|..   |.|.:..|...|||.:.:||..||.|||.|.|
  Fly   384 MTGFKLEEFPAIQLANFGVGGYFKPHYDFYTDRLKEVDVNNTLGDRIGSIIFYAGEVSQGGQTVF 448

  Fly   465 PRLNLTVFPQPGSALFWYNLDTKGNDHMGSLHTGCPVIVGSKWVMSKWINDMGQEFTRPC 524
            |.|.:.|.|:.|:||||:|..........|||:.|||:|||:|.::||::...|.|.:||
  Fly   449 PDLKVAVEPKKGNALFWFNAFDDSTPDPRSLHSVCPVLVGSRWTITKWLHYAPQLFVKPC 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE2	NP_733378.1	P4Ha_N	33..163	CDD:462433	36/132 (27%)
		TPR repeat	175..200	CDD:276809	5/24 (21%)
		TPR_16	176..254	CDD:433202	13/84 (15%)
		NrfG	217..>260	CDD:443378	8/49 (16%)
		TPR repeat	219..249	CDD:276809	5/30 (17%)
		P4Hc	342..513	CDD:214780	57/173 (33%)
CG18233	NP_649044.3	P4Ha_N	34..164	CDD:462433	35/131 (27%)
		P4Hc	333..498	CDD:214780	58/174 (33%)