DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaNE2 and phy-4

DIOPT Version :9

Sequence 1:	NP_733378.1	Gene:	PH4alphaNE2 / 43628	FlyBaseID:	FBgn0039783	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_001123049.1	Gene:	phy-4 / 189869	WormBaseID:	WBGene00012815	Length:	282	Species:	Caenorhabditis elegans

Alignment Length:	223	Identity:	63/223 - (28%)
Similarity:	109/223 - (48%)	Gaps:	21/223 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   324 KTEILSIDPFVVLLHDMISQK-------ESTLIRTSSKEHMLPSATTDPDASDDETQVDTYRTSK 381
            |.||||.:||::..|:.:.::       |:..:|.  ::..:...||.|:.|    ||   |.:.
Worm    63 KVEILSSEPFILQYHNQVHRRLAKRAVQEAEALRL--EQLKISGFTTTPEKS----QV---RAAN 118

  Fly   382 SVWYSSDFNDTTKKITERL-GDATGLDMNSTEFYQVINYGLGGFFETHLDMLLSEKN--RFNGTS 443
            ..|.......:..:|.|.| .:...||:::.|.:|:::|...|::..|.|.|....|  ...|..
Worm   119 GTWLIHTGRPSFARIFEGLQANINSLDLSTAEPWQILSYNADGYYAPHYDYLNPATNVQLVEGRG 183

  Fly   444 DRIATTLFYLNEVRQGGGTYFPRLNLTVFPQPGSALFWYNLDTKGNDHMGSLHTGCPVIVGSKWV 508
            :||||.|..|...::||.|.||||||.:.|:.|..:.|.|..:.|..:..:||..||:..|:|..
Worm   184 NRIATVLVILQIAKKGGTTVFPRLNLNIRPKAGDVIVWLNTLSTGESNSQTLHAACPIHEGTKIG 248

  Fly   509 MSKWINDMGQEFTRPCVESSLSSNEVLS 536
            .:.|:::  :.|::....:.||....|:
Worm   249 ATLWVHE--KIFSQNTKSTGLSRQNSLA 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE2	NP_733378.1	P4Ha_N	33..161	CDD:285528
		TPR repeat	175..200	CDD:276809
		TPR_16	176..254	CDD:290168
		TPR repeat	219..249	CDD:276809
		TPR_2	220..253	CDD:285020
		P4Hc	342..513	CDD:214780	50/180 (28%)
phy-4	NP_001123049.1	P4Hc	81..254	CDD:214780	51/181 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910