Protein Alignment CG15539 and p4ha2

DIOPT Version :10

• Sequence 1: NP_001036776.1
• Gene: CG15539 / 43627
• FlyBaseID: FBgn0039782
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_012814344.2
• Gene: p4ha2 / 493342
• XenbaseID: XB-GENE-957618
• Length: 537
• Species: Xenopus tropicalis
• Alignment Length: 561
• Identity: 168/561 - (29%)
• Similarity: 269/561 - (47%)
• Gaps: 87/561 - (15%)

  Fly     6 ISLAILYLLVLVKSHSKPKILENNYAISIYDMSKLIDYEHYLLNILQKFANALQKRVDTLEYYLE 70
            |||.:|.|..:.:       ::.....|...|:.||..|..||..|:::....::|:..::.:..
 Frog     6 ISLILLSLCCIWE-------VQTEVFTSTGQMTDLIFRERDLLQSLKEYIREEEERLSKIKRWAS 63

  Fly    71 MTDYDREKNLAE------DPIKHFRITRRLHSDYVNWVWFMEEQPWGTLVKDIIAIAPE------ 123
            ..|....::.|:      .|:..:::.:|.::|            |.:|...::..:.:
 Frog    64 EVDELSSRSTADPEGYLGHPVNAYKLVKRFNTD------------WSSLENLVLQDSAKGFIANF 116

  Fly   124 ------MPTLKDVEEAIRGLRLIQWTYSLPTAEMAKGVLQDIHHNTSLDGMQCITIARHMVNYKD 182
                  .||.:|...|.|.|..||.||.|....:|||.|...::.:||.......:.:...:..|
 Frog   117 TFQREYFPTEEDETGAARALMRIQDTYKLDPDVIAKGKLPGTNYISSLSADDSFGMGKIAYHDGD 181

  Fly   183 FIRAKEWLMVGLKMYEADEEIEYIYSQLGMPLVDF--YELFVEIQD-----ELGSRYLAMS-ELQ 239
            :.....|:...||  :.||..:.:.::  :.::|:  |.:| ::.|     ||..|.||:. ...
 Frog   182 YYHTVLWMQQALK--QMDEGEDAVVNK--VDVLDYLSYTVF-QLGDVPRALELTKRLLALDPNHD 241

  Fly   240 LAIKN--WPEKVSLQRALSRLKMNIRIGKEPAEKKN----------KSKRVYKKCCSSE-----C 287
            .|:.|  :.||:. ::..:.||.|.....|.|.::.          ..:.||:..|..|     .
 Frog   242 RAVNNLKYFEKMQ-EKQKAELKQNESTNTESATRQPGVYSRPLDYLPERDVYEALCRGEGVKMNP 305

  Fly   288 RPTAKLYCLYKT-TSSYFLRLAPLKMELLSLDPYMVLFHDVVSDKDIVSIRNLTKGKLAR-TVTV 350
            |...:|:|.|.. ..|.:|.|:|:|:|.....|.:|.:.:.:||::|..|:.|.|.|||| ||..
 Frog   306 RRQRRLFCRYHNGNRSPYLILSPVKVEDEWDSPRIVRYLNALSDEEIAKIKELAKPKLARATVRD 370

  Fly   351 SKDG-----NYTEDPDRTTKGTWLVEN-NALIQRLSQLTQDMTNFDIHDADPFQVLNYGIGGFYG 409
            .|.|     ||     |.:|..||.|| :.:|.|::...|.:|...:..|:..||.|||:||.|.
 Frog   371 PKTGVLSVANY-----RVSKSAWLEENDDPVIARVNLRMQAITGLTVDTAELLQVANYGMGGQYE 430

  Fly   410 IHFDFLEDAELDNF-----SDRIATAVFYLSDVPQGGATIFPKLGLSVFPKKGSALLWYNLDHKG 469
            .||||....|.|.|     .:|:||.:.|:|||..||||:||..|.:::||||:|:.||||...|
 Frog   431 PHFDFSRKDEPDVFKRLGTGNRVATFLNYMSDVEAGGATVFPDFGAAIWPKKGTAVFWYNLFRSG 495

  Fly   470 DGDNRTAHSACPTVVGSRWVMTKWINEREQIFRRPC-LTSI 509
            :||.||.|:|||.:|||:||..||.:||.|.|.||| ||.:
 Frog   496 EGDYRTRHAACPVLVGSKWVSNKWFHERGQEFLRPCGLTEV 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15539	NP_001036776.1	P4Ha_N	33..158	CDD:462433	31/142 (22%)
		P4Hc	329..494	CDD:214780	80/176 (45%)
p4ha2	XP_012814344.2	P4Ha_N	26..157	CDD:462433	31/142 (22%)
		BepA	166..>247	CDD:443813	16/85 (19%)
		TPR repeat	166..201	CDD:276809	6/36 (17%)
		TPR repeat	206..236	CDD:276809	8/32 (25%)
		P4Hc	348..521	CDD:214780	81/177 (46%)