DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15539 and CG34041

DIOPT Version :9

Sequence 1:	NP_001036776.1	Gene:	CG15539 / 43627	FlyBaseID:	FBgn0039782	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_001034077.5	Gene:	CG34041 / 3885583	FlyBaseID:	FBgn0054041	Length:	568	Species:	Drosophila melanogaster

Alignment Length:	352	Identity:	84/352 - (23%)
Similarity:	166/352 - (47%)	Gaps:	51/352 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LLISLAILYLLVLVKSHSKPKILENNYAISIYDMSKLIDYEHYLLNILQKFANALQKRVDTLE-- 66
            |.:.|.|:||     |:|..   ||.:::|...:..::..:..::..|:.:..||:.::.|::
  Fly   239 LSVGLIIVYL-----SYSNS---ENRHSLSKSKVINILKIQENVVKYLENYIYALETKLKTIDEA 295

  Fly    67 ------YYLEMTDYDREK-NLAEDPIKHFRITRRLHSDYVNWVWFMEEQPWGTLVKDIIAIAPEM 124
                  |:::   ::|:| .:|..|:..:.:...:.||:.:|..|::|.|....:..:::|...:
  Fly   296 LIDLATYHIQ---FERDKLAIASSPVASYSLIHHMQSDWTHWQLFLQEDPGKDELASLMSIKKYL 357

  Fly   125 PTLKDVEEAIRGLRLIQWTYSLPTAEMAKGVL------------------QDIHHNTSLDGMQ-C 170
            ||..|:.|...|:..:...|.:...::|.||:                  .:|..|..|..:: |
  Fly   358 PTKNDISEVCHGISKMLNAYLMTAQDIANGVILGTQTKYISSALKLEYLYMEIICNRHLMSLRDC 422

  Fly   171 ITIARHMVNYKDFIRAKEWLMVGLKMYEADEEIEYIYSQLGMPLVDFYELFVEIQDELGSRYLAM 235
            :.::.|.:..||:.::||||.|.:.|.|:....:.|     :|..|.|....|:..:..:..||:
  Fly   423 VALSDHSMEMKDYNKSKEWLNVAISMLESSAYWDPI-----VPSADLYLKLAEVYVKQQNWTLAL 482

  Fly   236 SELQLAIKNWPEKVSLQRALSRLKMNIRIGKEPAEKKNKSKRVYKKCCSSECRPTAKLYCLYKT- 299
            ..::.|:|:.|....|.|...||..:|.:|...:.|.|.....|:      .|....|||.|.|
  Fly   483 ETVEFALKSNPRNAQLIRMQKRLSYHILLGPPKSPKLNIENNDYR------LRKNGSLYCFYDTK 541

  Fly   300 TSSYFLRLAPLKMELLSLDPYMVLFHD 326
            ..:::..|||:|.|:|.:||.::|:|:
  Fly   542 IRTFYSLLAPIKAEVLFIDPLVILYHE 568

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15539	NP_001036776.1	P4Ha_N	33..156	CDD:285528	25/131 (19%)
CG15539	NP_001036776.1	P4Hc	329..494	CDD:214780
CG34041	NP_001034077.5	P4Ha_N	29..138	CDD:285528
		P4Ha_N	260..389	CDD:285528	25/131 (19%)
		TPR repeat	452..491	CDD:276809	8/43 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461989
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840