Protein Alignment CG15539 and P4ha1

DIOPT Version :10

• Sequence 1: NP_001036776.1
• Gene: CG15539 / 43627
• FlyBaseID: FBgn0039782
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_035160.1
• Gene: P4ha1 / 18451
• MGIID: 97463
• Length: 534
• Species: Mus musculus
• Alignment Length: 554
• Identity: 168/554 - (30%)
• Similarity: 268/554 - (48%)
• Gaps: 73/554 - (13%)

  Fly     5 LISLAILYLLVLVKSHSKPKILENNYAISIYDMSKLIDYEHYLLNILQKFANALQKRVDTLEYYL 69
            :|.:.::..::|.:|.:.|     .:..||..|:.||..|..|:..|:.:..|.:.:::.::.:.
Mouse     1 MIWVVLMMAILLPQSLAHP-----GFFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWA 60

  Fly    70 EMTD-------YDREKNLAEDPIKHFRITRRLHSDYVNWVWFMEEQPWGTLVKDI-------IAI 120
            |..|       .|.| .....|:..|::.:||:::     |...|   ..::||:       :.|
Mouse    61 EKLDRLTSTATKDPE-GFVGHPVNAFKLMKRLNTE-----WSELE---NLILKDMSDGFISNLTI 116

  Fly   121 APE-MPTLKDVEEAIRGLRLIQWTYSLPTAEMAKGVLQDIHHNTSLDGMQCITIARHMVNYKDFI 184
            ..: .|..:|...|.:.|..:|.||:|.|..::||.|..:.|.:.|....|..:.:......|:.
Mouse   117 QRQYFPNDEDQVGAAKALFRLQDTYNLDTNTISKGNLPGVQHKSFLTAEDCFELGKVAYTEADYY 181

  Fly   185 RAKEWLMVGLKMYEADE--------EIEY----IYSQ--LGMPLV---DFYELFVEIQDELGS-- 230
            ..:.|:...|...|..|        .::|    :|.|  |...|:   ...||..|.|...|:
Mouse   182 HTELWMEQALTQLEEGELSTVDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLV 246

  Fly   231 --RYLAMSELQLAIKNWPEKVSLQRALSRLKMNIRIGKEPAEKKNKSKRVYKKCCSSE-----CR 288
              .|: ||:.:.|.|:.....|.|:...: |..|.:...|..:|      |:..|..|     .|
Mouse   247 YFEYI-MSKEKDANKSASGDQSDQKTAPK-KKGIAVDYLPERQK------YEMLCRGEGIKMTPR 303

  Fly   289 PTAKLYCLYK--TTSSYFLRLAPLKMELLSLDPYMVLFHDVVSDKDIVSIRNLTKGKLAR-TVTV 350
            ...:|:|.|.  ..:..|: |||.|.|.....|.::.|||::||.:|..:::|.|.:|.| |::.
Mouse   304 RQKRLFCRYHDGNRNPKFI-LAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLRRATISN 367

  Fly   351 SKDGNYTEDPDRTTKGTWLV-ENNALIQRLSQLTQDMTNFDIHDADPFQVLNYGIGGFYGIHFDF 414
            ...|.......|.:|..||. ..:.::.|::...||:|..|:..|:..||.|||:||.|..||||
Mouse   368 PVTGALETVHYRISKSAWLSGYEDPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDF 432

  Fly   415 LEDAELDNF-----SDRIATAVFYLSDVPQGGATIFPKLGLSVFPKKGSALLWYNLDHKGDGDNR 474
            ....|.|.|     .:||||.:||:|||..||||:||::|.||:||||:|:.||||...|:||..
Mouse   433 ARKDEPDAFRELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYS 497

  Fly   475 TAHSACPTVVGSRWVMTKWINEREQIFRRPCLTS 508
            |.|:|||.:||::||..||::||.|.|||||..|
Mouse   498 TRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLS 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15539	NP_001036776.1	P4Ha_N	33..158	CDD:462433	34/139 (24%)
		P4Hc	329..494	CDD:214780	74/171 (43%)
P4ha1	NP_035160.1	P4Ha_N	24..155	CDD:462433	34/139 (24%)
		TPR	205..238		7/32 (22%)
		P4Hc	345..518	CDD:214780	75/172 (44%)