DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31371 and CG31016

DIOPT Version :9

Sequence 1:	NP_733375.2	Gene:	CG31371 / 43626	FlyBaseID:	FBgn0051371	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_001263119.1	Gene:	CG31016 / 326113	FlyBaseID:	FBgn0051016	Length:	536	Species:	Drosophila melanogaster

Alignment Length:	545	Identity:	122/545 - (22%)
Similarity:	219/545 - (40%)	Gaps:	116/545 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VVFSVLWLLQLFLLVESVAG-ANFARGEEQLQALLDTETQLIDGLRDYIERLERQLEEIRRETSA 66
            |:|:|.::|.|..:.|.... .|:....|:...||:.:.:||..|..|...|..::..::|   .
  Fly     5 VLFAVSFILVLSWIAEGYRDRQNYVISVEEKMDLLEKDRELIIVLDSYATELNEKIIMLKR---I 66

  Fly    67 IEEIHSQVDSV----EEYMGNPLNVFGILKRFESVWPGLEQKANATLEMVFGER----LSDRQLT 123
            ::|....::..    |||:.||::...::::....|    :|....|:...|:.    :...:..
  Fly    67 VKEFKQPLEKAKNREEEYLSNPIDSLSLMRQMHEDW----EKVEKLLKKPVGQEKIALVEKMRED 127

  Fly   124 LPSEEDYEESLNHLLHLQSVYELDSNSLSLGVVNGFKLGSSMSWGDCLEVARKS----DFPVARF 184
            ||.|.|..|:...:..:...|:|:...:|.|.::|.:.|..||..||..:...|    .:.:|..
  Fly   128 LPVENDLMEANQAMFRILHTYDLEPKDVSAGWIDGVQYGGKMSASDCFTMGTFSFMAGSYQIASK 192

  Fly   185 WLESALEKLPSASENSTE-------------SQRERESGRVHILEATLNIEYRAGELSRALATAE 236
            ||.:|.:.|........|             ::....||.|.|....|..::..||...|| |..
  Fly   193 WLSAAKDLLVDQPRKYHEVMGITKADVTLLLARSLIASGNVSIATDMLMRDFMFGEAGSAL-TVH 256

  Fly   237 ELLLLLPMNQGIQKAKRKIEKAMAKKELPKGRGQKSKAKKQIS----KSTEQLLIEEICRGAKQQ 297
            .|                                ::|.|..|:    :|.|.  ..::||.:.::
  Fly   257 FL--------------------------------RNKPKPSINLESWESDES--FNQLCRSSSRR 287

  Fly   298 VTTGSRFN--HCQLDG-SSPWLLLQPSRLEPVSSDPYIVLHHDVLTPKESNELLQL--------- 350
            ....|:.:  ||:.:. ::|:|.|.|.|:|.:|.|||::.:|:||:..|..:|..:
  Fly   288 QMGESKPSRLHCRYNTITTPFLKLAPFRMEELSLDPYVIFYHNVLSDAEIEKLKPMGKPFLERAK 352

  Fly   351 ----------IDEEEDTKG--VSYQSLKLSKLAQKKLGRISRLLGLEILELDPWTGRR------- 396
                      ||......|  :.:|::....|  :.|.||.|.:. ::..|:..:|.:
  Fly   353 VFRVEKGSDEIDPSRSADGAWLPHQNIDPDDL--EVLNRIGRRIE-DMTGLNTRSGSKMQFLKYG 414

  Fly   397 -HGH-----EHITKLEHSSEL--KHVARLMLNLQAPGMGGAVVFPQLELAVNVPRGSLLHWRTRF 453
             .||     ::......|.|.  ..:|.::..|.....|||.|||:|.|||...:||.|.|..
  Fly   415 FGGHFVPHYDYFNSKTFSLETVGDRIATVLFYLNNVDHGGATVFPKLNLAVPTQKGSALFWHN-- 477

  Fly   454 AGGSSSEWDYRSGQAICPVLLGVQL 478
            ....|.::|.|:....||::.|.:|
  Fly   478 IDRKSYDYDTRTFHGACPLISGTKL 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31371	NP_733375.2	P4Ha_N	30..156	CDD:285528	28/133 (21%)
CG31016	NP_001263119.1	P4Ha_N	31..160	CDD:285528	28/135 (21%)
CG31016	NP_001263119.1	P4Hc	333..508	CDD:214780	40/175 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461918
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D391515at2759
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	7	6.850