Protein Alignment CG31371 and P4HA3

DIOPT Version :9

• Sequence 1: NP_733375.2
• Gene: CG31371 / 43626
• FlyBaseID: FBgn0051371
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_001275677.1
• Gene: P4HA3 / 283208
• HGNCID: 30135
• Length: 604
• Species: Homo sapiens
• Alignment Length: 550
• Identity: 139/550 - (25%)
• Similarity: 211/550 - (38%)
• Gaps: 137/550 - (24%)

  Fly    26 ARGE-----EQLQALLDTETQLIDGLRDYIERLERQLEEIRRETSAIEEIHSQVDSVEEYMGNPL 85
            |||:     ..:...|..|.:|:..||.|:...|.:|.::.|....:..:|.  ||... :.|||
Human    26 ARGDTFSALTSVARALAPERRLLGLLRRYLRGEEARLRDLTRFYDKVLSLHE--DSTTP-VANPL 87

  Fly    86 NVFGILKRFESVWPGLEQKANATLEMVFGERLSDR----QLTLPSEEDYEESLNHLLHLQSVYEL 146
            ..|.::||.:|.|..:.....|:..:   ..|.|.    :..||:.||.|.:...|:.||.||.|
Human    88 LAFTLIKRLQSDWRNVVHSLEASENI---RALKDGYEKVEQDLPAFEDLEGAARALMRLQDVYML 149

  Fly   147 DSNSLSLGV---VNGFKLGS--------SMSWGDCLEVAR----KSDFPVARFWLESALEKL-PS 195
            :...|:.||   |.|..:..        |::..||.:|.:    ..|:..|..|||.|:... .|
Human   150 NVKGLARGVFQRVTGSAITDLYSPKRLFSLTGDDCFQVGKVAYDMGDYYHAIPWLEEAVSLFRGS 214

  Fly   196 ASENSTESQRERESGRVHILEATLNIEYRAGELSRALATAEELLLLLPMNQGIQKAKRKIEKAMA 260
            ..|..||.:...|....|:..|    .:|||.:|.||:.:.|.||..|.|           |.||
Human   215 YGEWKTEDEASLEDALDHLAFA----YFRAGNVSCALSLSREFLLYSPDN-----------KRMA 264

  Fly   261 KKELPKGRGQKSKAKKQISKSTEQLLIEEICR--GAKQQVTTGSRFNHCQLDGSSP--------- 314
            :..|        |.::.:::|...::.|.:.:  ......|..:....||..||.|
Human   265 RNVL--------KYERLLAESPNHVVAEAVIQRPNIPHLQTRDTYEGLCQTLGSQPTLYQIPSLY 321

  Fly   315 ---------WLLLQPSRLEPVSSDPYIVLHHDVLTPKESNELLQL---------IDEEEDTKGVS 361
                     :|||||.|.|.:..:|||.|:||.::..|:.::.:|         :...|....|.
Human   322 CSYETNSNAYLLLQPIRKEVIHLEPYIALYHDFVSDSEAQKIRELAEPWLQRSVVASGEKQLQVE 386

  Fly   362 YQSLK---LSKLAQKKL----GRISRLLGLEILELDPWT-----------GRRHGH-EHITKLEH 407
            |:..|   |......||    .||:.|.||::  ..|:.           |....| :|.|  ..
Human   387 YRISKSAWLKDTVDPKLVTLNHRIAALTGLDV--RPPYAEYLQVVNYGIGGHYEPHFDHAT--SP 447

  Fly   408 SSEL------KHVARLMLNLQAPGMGGAVVFPQLELAVNVPR------------GSLLH------ 448
            ||.|      ..||..|:.|.:...|||..|....|:|.|.|            |::.|
Human   448 SSPLYRMKSGNRVATFMIYLSSVEAGGATAFIYANLSVPVVRHCFGGTCTGVVKGTVTHFMLAVL 512

  Fly   449 --WRTRFAGGSSSEW---DYRSGQAICPVL 473
              |  ..:|..:|.:   |..|.....|.|
Human   513 SWW--EISGWPTSGYMSMDRNSADPAAPAL 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31371	NP_733375.2	P4Ha_N	30..156	CDD:285528	37/132 (28%)
P4HA3	NP_001275677.1	P4Ha_N	58..159	CDD:285528	30/106 (28%)
		TPR_12	186..252	CDD:290160	20/69 (29%)
		P4Hc	356..>478	CDD:214780	29/125 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149283
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	6	5.700