DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PH4alphaNE1 and P4H5

DIOPT Version :9

Sequence 1:	NP_733374.1	Gene:	PH4alphaNE1 / 43625	FlyBaseID:	FBgn0039780	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_179363.1	Gene:	P4H5 / 816281	AraportID:	AT2G17720	Length:	291	Species:	Arabidopsis thaliana

Alignment Length:	208	Identity:	66/208 - (31%)
Similarity:	97/208 - (46%)	Gaps:	22/208 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   324 LEEHSLDPYVATFHDILSPGKISQLREMAVPRMHRSTVNPLPGGQLKKSAFRVSKNAWLAYESHP 388
            :|..|.:|....:|:.|:..:...|..:|.|.|.:|||.....|..|.|..|.|...:|. ..|.
plant    80 VEVISWEPRAVVYHNFLTNEECEHLISLAKPSMVKSTVVDEKTGGSKDSRVRTSSGTFLR-RGHD 143

  Fly   389 TMVGML-RDLKDATGLDTTFCEQLQVANYGVGGHYEPHWDFFRDPNHYPAEEGNRIATAIFYLSE 452
            .:|.:: :.:.|.|.:.....|.|||.:|.||..||||:|:|.| .......|.||||.:.|||:
plant   144 EVVEVIEKRISDFTFIPVENGEGLQVLHYQVGQKYEPHYDYFLD-EFNTKNGGQRIATVLMYLSD 207

  Fly   453 VEQGGATAFPFL-------------------DIAVKPQLGNVLFWYNLHRSLDKDYRTKHAGCPV 498
            |:.||.|.||..                   .::|.|:..:.|.::|:......|..:.|.||||
plant   208 VDDGGETVFPAARGNISAVPWWNELSKCGKEGLSVLPKKRDALLFWNMRPDASLDPSSLHGGCPV 272

  Fly   499 LKGSKWIGNVWIH 511
            :||:||....|.|
plant   273 VKGNKWSSTKWFH 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE1	NP_733374.1	P4Ha_N	26..155	CDD:285528
PH4alphaNE1	NP_733374.1	P4Hc	341..511	CDD:214780	60/189 (32%)
P4H5	NP_179363.1	PLN00052	75..290	CDD:177683	66/208 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.920