DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PH4alphaNE1 and Y43F8B.19

DIOPT Version :9

Sequence 1:	NP_733374.1	Gene:	PH4alphaNE1 / 43625	FlyBaseID:	FBgn0039780	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_001123044.2	Gene:	Y43F8B.19 / 6418801	WormBaseID:	WBGene00077688	Length:	243	Species:	Caenorhabditis elegans

Alignment Length:	210	Identity:	61/210 - (29%)
Similarity:	94/210 - (44%)	Gaps:	36/210 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   322 LKLEEHSLDPYVATFHDILSPGKISQLREMAVPRMH-----RSTVNPLPGGQLKKSAFRVSKNAW 381
            :|:|..:..|.:..:.|:.: ||  |:|:......|     :..||  ..|....|..|.:....
Worm    22 VKVEVVAWRPGLVIYRDLFT-GK--QVRDHLELMEHLKFEEQLVVN--DDGNDIVSKIRRANGTQ 81

  Fly   382 LAYESHP-------TMVGMLRDLKDATGLDTTFCEQLQVANYGVGGHYEPHWDFFRDPNHYPAEE 439
            :.:|.||       |...:|.:|...|      .|.:...:|..||||..|.|:..    ||:|:
Worm    82 VFHEDHPAARSIWDTAKNLLPNLNFKT------AEDILALSYNPGGHYAAHHDYLL----YPSEK 136

  Fly   440 ---------GNRIATAIFYLSEVEQGGATAFPFLDIAVKPQLGNVLFWYNLHRSLDKDYRTKHAG 495
                     |||..|.|......|.||||.||.|..||:.:.|:..||:|...:.:::..::|||
Worm   137 EWDEWMRVNGNRFGTLIMAFGAAESGGATVFPRLGAAVRTKPGDAFFWFNAMGNSEQEDLSEHAG 201

  Fly   496 CPVLKGSKWIGNVWI 510
            ||:.||.|.|..:|:
Worm   202 CPIYKGQKQISTIWL 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE1	NP_733374.1	P4Ha_N	26..155	CDD:285528
PH4alphaNE1	NP_733374.1	P4Hc	341..511	CDD:214780	57/191 (30%)
Y43F8B.19	NP_001123044.2	P4Hc	43..217	CDD:214780	56/188 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810