Protein Alignment PH4alphaNE1 and p4ha3

DIOPT Version :9

• Sequence 1: NP_733374.1
• Gene: PH4alphaNE1 / 43625
• FlyBaseID: FBgn0039780
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: XP_021322008.1
• Gene: p4ha3 / 563281
• ZFINID: ZDB-GENE-041010-4
• Length: 616
• Species: Danio rerio
• Alignment Length: 542
• Identity: 160/542 - (29%)
• Similarity: 260/542 - (47%)
• Gaps: 50/542 - (9%)

  Fly     6 LLVGLIFLLAQGSLASDYFSSITGLEDLLHTEQYLTRELRSKVNAIQTALQQLESELSSIEKEHT 70
            |.:.|..|........:.|:|:..:...:..|:.|...|...:......|:.::...|.:...|.
Zfish     7 LFIVLYLLNMPDESFGEMFTSMLSVNQAVSAERKLIDHLIIYIEHEAQRLEDIKRFFSRVTSLHD 71

  Fly    71 MAASDTENYLTNPVNVYRLMKRLHTDW------SLMEGRVQLMAEEMNFNATREYGLSYPSQEDV 129
            ...::..:.:.||:..::|:|||.::|      :..|..::::.|:.     |....|.|..||:
Zfish    72 GIYNEPSDPIANPIAAFKLVKRLKSEWLNVVHSTEAEENIKVLREDY-----RRMESSLPKLEDL 131

  Fly   130 EGAALALVRLQSTYKLDVAQVAQG----ILNGVKY----GSDM-SWQDCFELGQQLFEMEDYNNT 185
            .|||..|:|||..|.|.|..:.:|    |.:.|.:    .||| |..|||.:|:..:::|||.::
Zfish   132 RGAAHGLMRLQDVYNLHVESLVRGHFQQISDPVDFYKLSVSDMLSGDDCFLVGKVAYDLEDYYHS 196

  Fly   186 KVWLRESMERLRRQTSHAPSHLAPTSGPDTVTLNKMEATAKSLFQLGDFDTAFELSQRVLQFDPK 250
            .:|..|:: ||.|.|..:|.:       :....:.::..|.|.|:.|:...|..||:.:|..||.
Zfish   197 VLWFEEAV-RLFRGTEWSPEN-------EGTLEDALDHLAFSHFKTGNISHALSLSRELLLHDPM 253

  Fly   251 RIRNWHLGDKGTAPPEDIDDVYLPKHSDSYSLSQEFA-------KYEKVCR---GEVHPIVRQEL 305
            . |..|.   .....|.:.:..||..|...:|.:...       .||::|:   .:........|
Zfish   254 N-RRVHF---NVEKYEKLLNENLPATSSGLTLKRPDGIYLRTRNAYEQLCQTKGSQPKHFENPSL 314

  Fly   306 RCRYSRGNHPYRFLAPLKLEEHSLDPYVATFHDILSPGKISQLREMAVPRMHRSTVNPLPGGQLK 370
            .|.|.....|..||.|::.|..||.|||..||..::..:...:|:.|:|.:.||.|  ..|....
Zfish   315 FCDYFTNGSPALFLQPIRREIISLQPYVVLFHGFVTQAEAKNIRKYAMPGLRRSVV--ASGMNQA 377

  Fly   371 KSAFRVSKNAWLAYESHPTMVGMLRDLKDATGLDT--TFCEQLQVANYGVGGHYEPHWDFFRDPN 433
            .:.:|:||:|||...:|..:..:.:.:...|||:.  .:.|.|||.|||:|||||||:|.....:
Zfish   378 TAEYRISKSAWLKESAHEVVGKLDQRITLVTGLNVQPPYAEYLQVVNYGIGGHYEPHFDHATSDS 442

  Fly   434 H--YPAEEGNRIATAIFYLSEVEQGGATAFPFLDIAVKPQLGNVLFWYNLHRSLDKDYRTKHAGC 496
            .  |..:.|||:||.:.|||.|:.||:|||.:.:.:|.......|||:|||::...:..|.||||
Zfish   443 SPLYRLKTGNRVATIMIYLSPVQAGGSTAFIYANFSVPVVQNAALFWWNLHKNGQGNVDTLHAGC 507

  Fly   497 PVLKGSKW--IGNVWIHEVTQT 516
            ||:.|:||  ..|...|:||.|
Zfish   508 PVIVGNKWGMFKNKNFHKVTCT 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE1	NP_733374.1	P4Ha_N	26..155	CDD:285528	32/138 (23%)
		P4Hc	341..511	CDD:214780	65/175 (37%)
p4ha3	XP_021322008.1	P4Ha_N	27..157	CDD:311993	32/134 (24%)
		P4Hc	350..519	CDD:214780	64/170 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583395
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52324
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.960