Protein Alignment PH4alphaNE1 and p4ha1a

DIOPT Version :9

• Sequence 1: NP_733374.1
• Gene: PH4alphaNE1 / 43625
• FlyBaseID: FBgn0039780
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: XP_009304776.1
• Gene: p4ha1a / 562774
• ZFINID: ZDB-GENE-040724-91
• Length: 541
• Species: Danio rerio
• Alignment Length: 542
• Identity: 203/542 - (37%)
• Similarity: 314/542 - (57%)
• Gaps: 48/542 - (8%)

  Fly    10 LIFLLAQGSLASDYFSSITGLEDLLHTEQYLTRELRSKVNAIQTALQQLESELSSIEKEHTMAAS 74
            ||.||...|..||:|:||..:.|||.||:.|...|:..:.|.::.|:|::.....::.....|..
Zfish    12 LISLLKSSSAHSDFFTSIGHMTDLLFTEKDLVTSLKDYIKAEESKLEQVKQWAEKLDALTATAVQ 76

  Fly    75 DTENYLTNPVNVYRLMKRLHTDWSLMEGRVQLMAEEM------NFNATREYGLSYPSQEDVEGAA 133
            |.|.:|.:|||.::|||||:|:|..:|   .|:.::|      |....|:|   :|:.||..|||
Zfish    77 DPEGFLGHPVNAFKLMKRLNTEWGEVE---DLVLKDMSDGFISNLTIQRQY---FPNDEDQNGAA 135

  Fly   134 LALVRLQSTYKLDVAQVAQGILNGVK----YGSDMSWQDCFELGQQLFEMEDYNNTKVWLRESME 194
            .||:|||.|||||...::.|.|.||.    |.|.::.:||||||:..:...||.:|::|:.::::
Zfish   136 KALLRLQDTYKLDTQTISSGDLPGVNTGLPYKSTLTVEDCFELGKIAYSDADYYHTELWMAQALK 200

  Fly   195 RLRRQTSHAPSHLAPTSGPDTVTLNKMEATAKSLFQLGDFDTAFELSQRVLQFDPKRIR------ 253
            :|..         ...|..:..|  .::..:.|::|.|:.:.|.|.::|:|..:|:..|
Zfish   201 QLDE---------GEESSVEIAT--ALDYLSYSVYQQGELERALEYTKRLLTVEPEHQRALGNLK 254

  Fly   254 --NWHLGDKGTAPPEDIDDVYLPKHSDSYSLSQEF----AKYEKVCRGE---VHPIVRQELRCRY 309
              ::.|..:..|..|........|..::....:|:    .||||:||||   :.|..::.|.|||
Zfish   255 YFDYQLAKQKKAEKEQSTKEESKKEQETSDGKKEYLPEKRKYEKLCRGEGLKMTPRRQKHLFCRY 319

  Fly   310 SRGN-HPYRFLAPLKLEEHSLDPYVATFHDILSPGKISQLREMAVPRMHRSTV-NPLPGGQLKKS 372
            ..|| ||:..:.|:|.|:....|.:..:|:|::..:|.:::|::.||:.|:|: ||:. |.|:.:
Zfish   320 FNGNRHPFYTIGPVKQEDEWDRPRIIRYHEIITEQEIEKIKELSKPRLRRATISNPIT-GVLETA 383

  Fly   373 AFRVSKNAWLAYESHPTMVGMLRDLKDATGLDTTFCEQLQVANYGVGGHYEPHWDFFR--DPNHY 435
            .:|:||:||||...||.:..:.:.::|.|||:....|:||||||||||.||||:||.|  :|:.:
Zfish   384 HYRISKSAWLAAYEHPVVDRINQRIEDITGLNVKTAEELQVANYGVGGQYEPHFDFGRKDEPDAF 448

  Fly   436 -PAEEGNRIATAIFYLSEVEQGGATAFPFLDIAVKPQLGNVLFWYNLHRSLDKDYRTKHAGCPVL 499
             ....||||||.:||:|:|..||||.||.:..||||..|..:|||||..|.:.||.|:||.||||
Zfish   449 KELGTGNRIATWLFYMSDVAAGGATVFPEVGAAVKPLKGTAVFWYNLFPSGEGDYSTRHAACPVL 513

  Fly   500 KGSKWIGNVWIHEVTQTFARPC 521
            .|:||:.|.||||..|.|.|||
Zfish   514 VGNKWVSNKWIHERGQEFRRPC 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE1	NP_733374.1	P4Ha_N	26..155	CDD:285528	49/134 (37%)
		P4Hc	341..511	CDD:214780	83/173 (48%)
p4ha1a	XP_009304776.1	P4Ha_N	28..157	CDD:285528	49/134 (37%)
		TPR repeat	172..207	CDD:276809	11/43 (26%)
		TPR repeat	212..242	CDD:276809	8/31 (26%)
		Fis1	218..262	CDD:304536	10/43 (23%)
		P4Hc	352..525	CDD:214780	83/173 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583427
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52324
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.760