Protein Alignment PH4alphaNE1 and p4ha2

DIOPT Version :9

• Sequence 1: NP_733374.1
• Gene: PH4alphaNE1 / 43625
• FlyBaseID: FBgn0039780
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: XP_012814344.2
• Gene: p4ha2 / 493342
• XenbaseID: XB-GENE-957618
• Length: 537
• Species: Xenopus tropicalis
• Alignment Length: 551
• Identity: 197/551 - (35%)
• Similarity: 302/551 - (54%)
• Gaps: 68/551 - (12%)

  Fly    10 LIFLLAQGSLASDYFSSITGLEDLLHTEQYLTRELRSKVNAIQTALQQLESELSSIEKEHTMAAS 74
            |:.|.....:.::.|:|...:.||:..|:.|.:.|:..:...:..|.:::...|.:::..:.:.:
 Frog    10 LLSLCCIWEVQTEVFTSTGQMTDLIFRERDLLQSLKEYIREEEERLSKIKRWASEVDELSSRSTA 74

  Fly    75 DTENYLTNPVNVYRLMKRLHTDWSLMEGRV-QLMAEEM--NFNATREYGLSYPSQEDVEGAALAL 136
            |.|.||.:|||.|:|:||.:||||.:|..| |..|:..  ||...|||   :|::||..|||.||
 Frog    75 DPEGYLGHPVNAYKLVKRFNTDWSSLENLVLQDSAKGFIANFTFQREY---FPTEEDETGAARAL 136

  Fly   137 VRLQSTYKLDVAQVAQGILNGVKYGSDMSWQDCFELGQQLFEMEDYNNTKVWLRESMERLRRQTS 201
            :|:|.|||||...:|:|.|.|..|.|.:|..|.|.:|:..:...||.:|.:|::::::::
 Frog   137 MRIQDTYKLDPDVIAKGKLPGTNYISSLSADDSFGMGKIAYHDGDYYHTVLWMQQALKQM----- 196

  Fly   202 HAPSHLAPTSGPDTVTLNKMEA---TAKSLFQLGDFDTAFELSQRVLQFDP---KRIRNWHLGDK 260
                    ..|.|.| :||::.   .:.::|||||...|.||::|:|..||   :.:.|....:|
 Frog   197 --------DEGEDAV-VNKVDVLDYLSYTVFQLGDVPRALELTKRLLALDPNHDRAVNNLKYFEK 252

  Fly   261 -------------------GTAPP----EDIDDVYLPKHSDSYSLSQEFAKYEKVCRGE---VHP 299
                               .|..|    ..:|  |||:..          .||.:||||   ::|
 Frog   253 MQEKQKAELKQNESTNTESATRQPGVYSRPLD--YLPERD----------VYEALCRGEGVKMNP 305

  Fly   300 IVRQELRCRYSRGNH-PYRFLAPLKLEEHSLDPYVATFHDILSPGKISQLREMAVPRMHRSTVNP 363
            ..::.|.|||..||. ||..|:|:|:|:....|.:..:.:.||..:|::::|:|.|::.|:||..
 Frog   306 RRQRRLFCRYHNGNRSPYLILSPVKVEDEWDSPRIVRYLNALSDEEIAKIKELAKPKLARATVRD 370

  Fly   364 LPGGQLKKSAFRVSKNAWLAYESHPTMVGMLRDLKDATGLDTTFCEQLQVANYGVGGHYEPHWDF 428
            ...|.|..:.:||||:|||.....|.:..:...::..|||.....|.|||||||:||.||||:||
 Frog   371 PKTGVLSVANYRVSKSAWLEENDDPVIARVNLRMQAITGLTVDTAELLQVANYGMGGQYEPHFDF 435

  Fly   429 FR--DPNHYP-AEEGNRIATAIFYLSEVEQGGATAFPFLDIAVKPQLGNVLFWYNLHRSLDKDYR 490
            .|  :|:.:. ...|||:||.:.|:|:||.||||.||....|:.|:.|..:|||||.||.:.|||
 Frog   436 SRKDEPDVFKRLGTGNRVATFLNYMSDVEAGGATVFPDFGAAIWPKKGTAVFWYNLFRSGEGDYR 500

  Fly   491 TKHAGCPVLKGSKWIGNVWIHEVTQTFARPC 521
            |:||.||||.||||:.|.|.||..|.|.|||
 Frog   501 TRHAACPVLVGSKWVSNKWFHERGQEFLRPC 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE1	NP_733374.1	P4Ha_N	26..155	CDD:285528	49/131 (37%)
		P4Hc	341..511	CDD:214780	80/172 (47%)
p4ha2	XP_012814344.2	P4Ha_N	27..113	CDD:400573	26/85 (31%)
		TPR repeat	166..201	CDD:276809	8/47 (17%)
		TPR repeat	206..236	CDD:276809	11/29 (38%)
		P4Hc	348..521	CDD:214780	80/172 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010