Protein Alignment PH4alphaNE1 and CG18234

DIOPT Version :9

• Sequence 1: NP_733374.1
• Gene: PH4alphaNE1 / 43625
• FlyBaseID: FBgn0039780
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_649043.3
• Gene: CG18234 / 40024
• FlyBaseID: FBgn0265268
• Length: 515
• Species: Drosophila melanogaster
• Alignment Length: 537
• Identity: 136/537 - (25%)
• Similarity: 248/537 - (46%)
• Gaps: 76/537 - (14%)

  Fly    26 SITGLEDLLHTEQYLTRELRSKVNAIQTALQQLESELSSIEKEHTMAASDTENYLTNPVNVYRLM 90
            ||.|:::|:..|.:...|:.|...|::..:..:||.|..::.:..::..:.|.::.:|:|.:.|:
  Fly    27 SIAGMKELVDLEGFFISEMESYTAALKNKIDLMESLLQEVQSKREISRRNPEEFVAHPLNAFSLI 91

  Fly    91 KRLHTDWSLMEGRVQLMAEEMNFNATR--EYGL--SYPSQEDVEGAALALVRLQSTYKLDVAQVA 151
            :|||.||:..|   .||..::.....:  |.||  :.||..|:..|...::.||..|.|..:.:|
  Fly    92 RRLHEDWTQAE---LLMLNQVGLEHLQAIETGLEEAQPSDNDLNDAIGGIISLQQFYNLQPSDIA 153

  Fly   152 QGILNGVKYGSDMSWQDCFELGQQLFEMEDYNNTKV---WLRESMERLR-RQTSHAPSHLAPTSG 212
            .|:|.|.:|.:.::..:|..|.....   ::|..|.   |.:.:::... .:.......:.....
  Fly   154 NGLLMGQQYNASLTTLNCQALANACM---NFNYDKYALNWFKAAVDHYNDDRDGQVYREVFDFRL 215

  Fly   213 PD--------TVTLNKMEATAKSLFQLGDFDTAFELSQRVLQFDPKRIRNWHLGDKGTAPPEDID 269
            ||        .||....:|..|.|..:.|.|....|.::.: ::..:|              |:.
  Fly   216 PDLYINYTSVLVTKGFRKAAWKVLQDVADLDATLWLLRKDI-YEVGKI--------------DVP 265

  Fly   270 DVYLPKHSDSYSLSQEFAKYEKVCRGEVHPIVR-----QELRCRYSRGNHPYRFLAPLKLEEHSL 329
            |       .::.::..|         :|...:|     |.|.|.|.:....:..:||||:|..||
  Fly   266 D-------PTFIITPWF---------DVTGCLRVGQTSQHLSCHYEKNTSEFLRIAPLKVETLSL 314

  Fly   330 DPYVATFHDILSPGKISQLREMAVPRMHRSTVNPLPGGQLKKSAFRVSKNAWLA--YESHPTMVG 392
            .|::..:||::...:||:::.:::|    |..:||      :..:.:..|...|  .|.|.:.:.
  Fly   315 KPHIVLYHDVIYDSEISKVKNISLP----SLKSPL------RILYAIDYNLKFAKIREDHQSPLS 369

  Fly   393 MLRDLKDATGLDTTFCEQLQVANYGVGGHYEPHWDFFRDPNHYPAEEGNRIATAIFYLSEVEQGG 457
            :  .:||.||.|.......|:.|||:.|....|.|.. :.....||.|:|:.:.:|::::|.|||
  Fly   370 L--RIKDMTGEDVQEDTDFQIDNYGICGFRNFHTDNI-ELQDQTAELGDRLTSIMFFMNDVAQGG 431

  Fly   458 ATAFPFLDIAVKPQLGNVLFWYNLHRSLDKDYRTKHAGCPVLKGSKWIGNVWIHEVTQTFARPCD 522
            |.|||.|::.:.||.|:.|.|.||...:..:....|..|||:.||||....|:||..|.|:|||.
  Fly   432 ALAFPNLNLTIWPQKGSALVWRNLDHRMQPNQDLLHVSCPVVVGSKWTLVKWLHERPQMFSRPCT 496

  Fly   523 V---FRDHEVSLEYEII 536
            .   |:.|:.|:::..:
  Fly   497 TGRKFKSHDQSMKFRAL 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE1	NP_733374.1	P4Ha_N	26..155	CDD:285528	36/132 (27%)
		P4Hc	341..511	CDD:214780	52/171 (30%)
CG18234	NP_649043.3	P4Ha_N	27..157	CDD:285528	36/132 (27%)
		P4Hc	<371..485	CDD:214780	42/114 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461941
Domainoid	1	1.000	91	0.514	Domainoid score	I2609
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	9	8.900