Protein Alignment PH4alphaNE1 and CG4174

DIOPT Version :9

• Sequence 1: NP_733374.1
• Gene: PH4alphaNE1 / 43625
• FlyBaseID: FBgn0039780
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001034031.2
• Gene: CG4174 / 40023
• FlyBaseID: FBgn0036793
• Length: 473
• Species: Drosophila melanogaster
• Alignment Length: 521
• Identity: 125/521 - (23%)
• Similarity: 223/521 - (42%)
• Gaps: 112/521 - (21%)

  Fly    18 SLASDYFSSITGLEDL-LHTEQYLTRELRSKVNAIQTALQQLESELSSIEKEHTMAASDTENYLT 81
            :::|:...|:..|::. ::..|...:.|:..:..|:.|::|.|..|.|.:              |
  Fly    30 AISSESQLSLLKLKETHVNNLQSYKKVLKKHLQKIRRAIRQSEELLKSTK--------------T 80

  Fly    82 NPVNV---YRLMKRLHTDW----SLME---GRVQLMAEEMNFNATREYGLSYPSQEDVEGAALAL 136
            :|.|:   |::::.||.||    .|::   |..|:...:|...       ..|:..|.|.:..|:
  Fly    81 SPRNLIYGYKVLRHLHNDWPQYFRLLKKDLGLEQIAVSQMLLT-------QQPTSVDFEESMGAM 138

  Fly   137 VRLQSTYKLDVAQVAQGILNGVKYGSDMSW--QDCFELGQQLFEMEDYNNTKVWLRESMERLRRQ 199
            .|||:.|.||...:.:|.::. |..:..:|  .:|..||.....::|||.::.||..::
  Fly   139 HRLQTVYNLDSYAMTEGFIDD-KDKNIRNWSADECLMLGLMYLFLKDYNQSENWLELAL------ 196

  Fly   200 TSHAPSHLAPTSGPDTVTL------NKMEATAKSLFQLGDFDTAFELSQRVLQFDPKRIRNWHLG 258
                 .|......|:.:.:      |.:|:..::...||.:..|.:.:..:|..:|.  ..:.|
  Fly   197 -----YHYDDNVSPEVLKIKLWNYPNLLESLVEANKGLGHYFEAKKYANELLSINPN--HTYML- 253

  Fly   259 DKGTAPPEDIDDVYLPKHSDSYSLSQEFAKYEKVCRGEVHPIVRQELR------CRYSRGNHPYR 317
                        ..|||.....|...:..|.:||.:.:.....::..|      |||.... |:.
  Fly   254 ------------TQLPKLKHLQSNPAKLTKPKKVFQLQKEICSKRYRRKSGVLVCRYVDWT-PFL 305

  Fly   318 FLAPLKLEEHSLDPYVATFHDILSPGKISQLREMAVPRMHRSTVNPLPG------GQLKKSAFRV 376
            .|||||:||.|:.||::.|:..|....|..|:.::.|::.|  :..|.|      |.|..|...|
  Fly   306 KLAPLKMEELSMKPYISIFYGFLGQKDIEVLKNVSRPKLQR--IEHLSGNCSCKIGNLSTSLHDV 368

  Fly   377 SKNAWLAYESHPTMVGMLRDLKDATGLDTTFCEQLQVANYGVGGHYEPHWDFFRDPNHYPAEEGN 441
            .:..      :..::|:       ||......:.|:|.|||:.|:|.|     .:|..:     |
  Fly   369 VRKV------NELILGI-------TGFPLKGNQMLEVINYGIAGNYNP-----EEPKIH-----N 410

  Fly   442 RIATAIFYLSEVEQGGATAFPFLDIAVKPQLGNVLFWYNLHRSLDKDYRTKHAGCPVLKGSKWIG 506
            : |.|..:||...:||...||...:.|:|:.|::|.|.||.:||      .:..||:|||:.|:.
  Fly   411 K-ANAFIFLSNAGKGGEIVFPSRHLKVRPRKGSMLVWENLKKSL------IYHQCPILKGNMWVA 468

  Fly   507 N 507
            |
  Fly   469 N 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PH4alphaNE1	NP_733374.1	P4Ha_N	26..155	CDD:285528	33/139 (24%)
		P4Hc	341..511	CDD:214780	47/173 (27%)
CG4174	NP_001034031.2	P4Ha_N	33..157	CDD:285528	34/144 (24%)
		TPR repeat	169..197	CDD:276809	8/38 (21%)
		TPR repeat	202..245	CDD:276809	7/42 (17%)
		2OG-FeII_Oxy	<362..470	CDD:304390	39/138 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461875
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.990